Guardant Health, Inc.
MX ˙ BMV ˙ US40131M1099
SecurityMX:GH / Guardant Health, Inc.
InstitutionFred Alger Management, Llc
Latest Disclosed Ownership622,259 shares
Latest Disclosed Value $ 57,478,064
Fred Alger Management, Llc reports 5.53% increase in ownership of GH / Guardant Health, Inc.

On May 15, 2026 - Fred Alger Management, Llc filed a 13F-HR form disclosing ownership of 622,259 shares of Guardant Health, Inc. (MX:GH) valued at $57,478,064 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 17, 2026 disclosing 589,656 shares of Guardant Health, Inc.. This represents a change in shares of 5.53% during the quarter.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F Guardant Health Equity 40131M109 622,259 32,603 5.53 57,478 -4.56 0.1606
2026-02-17 2025-12-31 13F Guardant Health Equity 40131M109 589,656 -48,831 -7.65 60,227 50.98 0.2362
2025-11-14 2025-09-30 13F Guardant Health Equity 40131M109 638,487 264,808 70.87 39,893 105.14 0.1553
2025-08-14 2025-06-30 13F Guardant Health Equity 40131M109 373,679 -83,938 -18.34 19,446 -0.25 0.0870
2025-05-16 2025-03-31 13F Guardant Health Equity 40131M109 457,617 302,145 194.34 19,494 310.49 0.1110
2025-02-14 2024-12-31 13F Guardant Health Equity 40131M109 155,472 43 0.03 4,750 33.21 0.0226
2024-11-14 2024-09-30 13F GUARDANT HEALTH Common 40131M109 155,429 -43,039 -21.69 3,566 -37.79 0.0173
2024-08-14 2024-06-30 13F GUARDANT HEALTH Common 40131M109 198,468 64,206 47.82 5,732 106.97 0.0279
2024-05-15 2024-03-31 13F GUARDANT HEALTH Common 40131M109 134,262 82,946 161.64 2,770 99.50 0.0137
2024-02-14 2023-12-31 13F GUARDANT HEALTH Common 40131M109 51,316 -508 -0.98 1,388 -9.64 0.0075
2023-11-14 2023-09-30 13F GUARDANT HEALTH Common 40131M109 51,824 51,824 1,536 0.0081
2023-11-14 2023-09-30 13F GUARDANT HEALTH Common 40131M109 51,824 1,536
2023-08-14 2023-06-30 13F GUARDANT HEALTH Common 40131M109 0 -10,000 -100.00 0 -100.00
2023-05-16 2023-03-31 13F/A-1 GUARDANT HEALTH Common 40131M109 10,000 -478 -4.56 234 -17.89 0.0013
2023-05-15 2023-03-31 13F GUARDANT HEALTH Common 40131M109 10,000 -478 234 0.0012
2023-02-14 2022-12-31 13F GUARDANT HEALTH Common 40131M109 10,478 -103,268 -90.79 285 -95.35 0.0015
2022-11-15 2022-09-30 13F GUARDANT HEALTH Common 40131M109 113,746 -3,051 -2.61 6,123 29.94 0.0310
2022-08-15 2022-06-30 13F GUARDANT HEALTH Common 40131M109 116,797 -252,878 -68.41 4,712 -80.76 0.0220
2022-05-16 2022-03-31 13F GUARDANT HEALTH Common 40131M109 369,675 -1,380,516 -78.88 24,487 -86.01 0.0782
2022-02-14 2021-12-31 13F GUARDANT HEALTH Common 40131M109 1,750,191 -913,431 -34.29 175,054 -47.43 0.4385
2021-11-15 2021-09-30 13F GUARDANT HEALTH Common 40131M109 2,663,622 -141,172 -5.03 332,979 -4.41 0.7939
2021-08-16 2021-06-30 13F GUARDANT HEALTH Common 40131M109 2,804,794 167,305 6.34 348,327 -13.48 0.8222
2021-05-17 2021-03-31 13F GUARDANT HEALTH Common 40131M109 2,637,489 567,042 27.39 402,613 50.88 1.0534
2021-02-16 2020-12-31 13F GUARDANT HEALTH Common 40131M109 2,070,447 126,880 6.53 266,839 22.82 0.6942
2020-11-13 2020-09-30 13F GUARDANT HEALTH Common 40131M109 1,943,567 -147,548 -7.06 217,252 28.06 0.6307
2020-08-14 2020-06-30 13F GUARDANT HEALTH Common 40131M109 2,091,115 892,602 74.48 169,652 103.38 0.5589
2020-05-19 2020-03-31 13F/A-1 GUARDANT HEALTH Common 40131M109 1,198,513 -136,247 -10.21 83,417 -20.02 0.3666
2020-05-15 2020-03-31 13F GUARDANT HEALTH Common 40131M109 1,198,513 -136,247 83,417 367,014.3837
2020-02-14 2019-12-31 13F GUARDANT HEALTH Common 40131M109 1,334,760 1,077,513 418.86 104,298 535.19 0.3839
2019-11-14 2019-09-30 13F GUARDANT HEALTH Common 40131M109 257,247 -41,062 -13.76 16,420 -36.24 0.0644
2019-08-14 2019-06-30 13F GUARDANT HEALTH Common 40131M109 298,309 195,148 189.17 25,753 225.49 0.0989
2019-05-14 2019-03-31 13F GUARDANT HEALTH Common 40131M109 103,161 34,032 49.23 7,912 204.42 0.0315
2019-02-14 2018-12-31 13F GUARDANT HEALTH Common 40131M109 69,129 69,129 2,599 0.0120
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.