Ionis Pharmaceuticals, Inc.
MX ˙ BMV ˙ US4622221004
SecurityMX:IONS / Ionis Pharmaceuticals, Inc.
InstitutionCaptrust Financial Advisors
Latest Disclosed Ownership5,000 shares
Latest Disclosed Value $ 375,450
Captrust Financial Advisors reports 5.54% decrease in ownership of IONS / Ionis Pharmaceuticals, Inc.

On May 14, 2026 - Captrust Financial Advisors filed a 13F-HR form disclosing ownership of 5,000 shares of Ionis Pharmaceuticals, Inc. (MX:IONS) valued at $375,450 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 17, 2026 disclosing 5,293 shares of Ionis Pharmaceuticals, Inc.. This represents a change in shares of -5.54% during the quarter.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-14 2026-03-31 13F IONIS PHARMACEUTICALS INC COM Stock 462222100 5,000 -293 -5.54 375 -10.29 0.0006
2026-02-17 2025-12-31 13F IONIS PHARMACEUTICALS INC COM Stock 462222100 5,293 5,293 419 0.0008
2024-05-15 2024-03-31 13F IONIS PHARMACEUTICALS INC COM Stock 462222100 0 -10,108 -100.00 0 -100.00
2024-02-14 2023-12-31 13F IONIS PHARMACEUTICALS INC COM Stock 462222100 10,108 -158 -1.54 511 9.89 0.0018
2023-11-15 2023-09-30 13F IONIS PHARMACEUTICALS INC COM Stock 462222100 10,266 939 10.07 466 21.73 0.0018
2023-08-15 2023-06-30 13F IONIS PHARMACEUTICALS INC COM Stock 462222100 9,327 -131 -1.39 383 13.02 0.0015
2023-05-15 2023-03-31 13F IONIS PHARMACEUTICALS INC COM Stock 462222100 9,458 -70 -0.73 338 -5.85 0.0015
2023-02-15 2022-12-31 13F IONIS PHARMACEUTICALS INC COM Stock 462222100 9,528 9,528 360 0.0018
2022-11-16 2022-09-30 13F IONIS PHARMACEUTICALS INC COM Common Stock 462222100 0 -1,429 -100.00 0 -100.00
2022-08-23 2022-06-30 13F/A-1 IONIS PHARMACEUTICALS INC COM Common Stock 462222100 1,429 249 21.10 53 20.45 0.0003
2022-08-16 2022-06-30 13F IONIS PHARMACEUTICALS INC COM COM 462222100 2,299 1,119 85 0.0006
2022-05-16 2022-03-31 13F IONIS PHARMACEUTICALS COM 462222100 1,180 -121 -9.30 44 10.00 0.0003
2022-02-14 2021-12-31 13F IONIS PHARMACEUTICALS INC COM Common Stock 462222100 1,301 -1,171 -47.37 40 -51.81 0.0003
2021-11-16 2021-09-30 13F IONIS PHARMACEUTICALS INC COM Common Stock 462222100 2,472 576 30.38 83 9.21 0.0007
2021-08-16 2021-06-30 13F IONIS PHARMACEUTICALS INC COM Common Stock 462222100 1,896 -77 -3.90 76 -14.61 0.0007
2021-05-17 2021-03-31 13F IONIS PHARMACEUTICALS INC COM Common Stock 462222100 1,973 420 27.04 89 1.14 0.0010
2021-02-16 2020-12-31 13F IONIS PHARMACEUTICALS INC COM Common Stock 462222100 1,553 0 0.00 88 18.92 0.0012
2020-11-17 2020-09-30 13F IONIS PHARMACEUTICALS INC COM Common Stock 462222100 1,553 0 0.00 74 -20.43 0.0012
2020-08-14 2020-06-30 13F IONIS PHARMACEUTICALS INC COM Common Stock 462222100 1,553 104 7.18 93 36.76 0.0015
2020-05-15 2020-03-31 13F IONIS PHARMACEUTICALS INC COM Common Stock 462222100 1,449 1,449 68 0.0015
2020-02-14 2019-12-31 13F IONIS PHARMACEUTICALS INC COM Common Stock 462222100 0 -496 -100.00 0 -100.00
2019-11-14 2019-09-30 13F IONIS PHARMACEUTICALS INC COM Common Stock 462222100 496 300 153.06 30 130.77 0.0011
2019-08-13 2019-06-30 13F IONIS PHARMACEUTICALS INC COM Common Stock 462222100 196 154 366.67 13 333.33 0.0005
2019-05-15 2019-03-31 13F IONIS PHARMACEUTICALS INC COM Common Stock 462222100 42 -44 -51.16 3 -40.00 0.0001
2019-02-13 2018-12-31 13F IONIS PHARMACEUTICALS INC COM Common Stock 462222100 86 0 0.00 5 25.00 0.0003
2018-11-15 2018-09-30 13F IONIS PHARMACEUTICALS INC COM Common Stock 462222100 86 0 0.00 4 0.00 0.0002
2018-08-13 2018-06-30 13F IONIS PHARMACEUTICALS INC COM Common Stock 462222100 86 86 4 0.0002
2018-05-15 2018-03-31 13F IONIS PHARMACEUTICALS INC COM Common Stock 462222100 0 -86 -100.00 0 -100.00
2018-02-14 2017-12-31 13F IONIS PHARMACEUTICALS INC COM Common Stock 462222100 86 0 0.00 4 0.00 0.0002
2018-02-16 2017-09-30 13F/A-1 IONIS PHARMACEUTICALS INC COM Common Stock 462222100 86 86 4 0.0003
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.