Cabaletta Bio, Inc.
US ˙ NasdaqGS ˙ US12674W1099

SecurityCABA / Cabaletta Bio, Inc.
InstitutionBarclays Plc
Latest Disclosed Ownership220,696 shares
Latest Disclosed Value $ 483,323
Barclays Plc reports 7,058.48% increase in ownership of CABA / Cabaletta Bio, Inc.

On February 13, 2026 - Barclays Plc filed a 13F-HR form disclosing ownership of 220,696 shares of Cabaletta Bio, Inc. (US:CABA) valued at $483,324 USD as of December 31, 2025. The entity filed a previous 13F-HR/A on March 31, 2026 disclosing 3,083 shares of Cabaletta Bio, Inc.. This represents a change in shares of 7,058.48% during the quarter. The current value of the position is $774,643 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-02-13 2025-12-31 13F CABALETTA BIO COM 12674W109 220,696 217,613 7,058.48 483 6,800.00 0.0001
2026-03-31 2025-09-30 13F/A-3 CABALETTA BIO COM 12674W109 3,083 -6,654 -68.34 7 -50.00 0.0000
2026-03-19 2025-09-30 13F/A-2 CABALETTA BIO COM 12674W109 61,130 51,393 289 0.0001
2025-11-12 2025-09-30 13F CABALETTA BIO COM 12674W109 3,083 -6,654 7 0.0000
2026-02-27 2025-06-30 13F/A-2 CABALETTA BIO COM 12674W109 9,737 -46,701 -82.75 15 -82.05 0.0000
2025-08-14 2025-06-30 13F/A-1 CABALETTA BIO COM 12674W109 9,737 -46,701 0 0.0000
2025-08-13 2025-06-30 13F CABALETTA BIO COM 12674W109 9,737 -46,701 0 0.0000
2026-03-17 2025-03-31 13F/A-1 CABALETTA BIO COM 12674W109 56,438 -15,179 -21.19 78 -51.85 0.0000
2025-05-15 2025-03-31 13F CABALETTA BIO COM 12674W109 56,438 -15,179 0 0.0000
2026-03-19 2024-12-31 13F/A-1 CABALETTA BIO COM 12674W109 71,617 10,487 17.16 163 -43.75 0.0000
2025-02-13 2024-12-31 13F CABALETTA BIO COM 12674W109 71,617 10,487 0 0.0000
2026-03-31 2024-09-30 13F/A-2 CABALETTA BIO COM 12674W109 61,130 19,891 48.23 289 -6.49 0.0001
2024-11-19 2024-09-30 13F/A-1 CABALETTA BIO COM 12674W109 61,130 19,891 0 0.0001
2024-11-15 2024-09-30 13F CABALETTA BIO COM 12674W109 61,130 19,891 0 0.0000
2026-03-23 2024-06-30 13F/A-1 CABALETTA BIO COM 12674W109 41,239 -7,729 -15.78 308 -63.11 0.0001
2024-08-14 2024-06-30 13F CABALETTA BIO COM 12674W109 41,239 -7,729 0 0.0001
2026-03-24 2024-03-31 13F/A-1 CABALETTA BIO COM 12674W109 48,968 -80,104 -62.06 835 -71.49 0.0003
2024-05-15 2024-03-31 13F CABALETTA BIO COM 12674W109 48,968 -80,104 1 0.0003
2026-03-25 2023-12-31 13F/A-1 CABALETTA BIO COM 12674W109 129,072 64,486 99.85 2,930 198.27 0.0011
2024-02-15 2023-12-31 13F CABALETTA BIO COM 12674W109 129,072 64,486 3 0.0011
2026-03-26 2023-09-30 13F/A-1 CABALETTA BIO COM 12674W109 64,586 59,490 1,167.39 983 1,410.77 0.0006
2023-11-07 2023-09-30 13F CABALETTA BIO COM 12674W109 64,586 59,490 1 0.0006
2026-03-30 2023-06-30 13F/A-2 CABALETTA BIO COM 12674W109 5,096 -62,102 -92.42 66 -88.29 0.0000
2023-09-20 2023-06-30 13F/A-1 CABALETTA BIO COM 12674W109 5,096 -62,102 0 0.0000
2023-08-03 2023-06-30 13F CABALETTA BIO COM 12674W109 5,096 -62,102 0 0.0000
2026-03-30 2023-03-31 13F/A-1 CABALETTA BIO COM 12674W109 67,198 63,052 1,520.79 556 1,360.53 0.0003
2023-05-04 2023-03-31 13F CABALETTA BIO COM 12674W109 67,198 63,052 1 0.0003
2026-03-30 2022-12-31 13F/A-1 CABALETTA BIO COM 12674W109 4,146 2,925 239.56 38 3,700.00 0.0000
2023-02-13 2022-12-31 13F CABALETTA BIO COM 12674W109 4,146 2,925 0 0.0000
2022-11-03 2022-09-30 13F CABALETTA BIO COM 12674W109 1,221 -13,942 -91.95 1 -93.75 0.0000
2022-08-12 2022-06-30 13F CABALETTA BIO COM 12674W109 15,163 -556 -3.54 16 -50.00 0.0000
2022-05-16 2022-03-31 13F CABALETTA BIO COM 12674W109 15,719 15,719 32 0.0000
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.