Opus Genetics, Inc.
US ˙ NasdaqCM ˙ US67577R1023
ESTE SÍMBOLO NÃO ESTÁ MAIS ATIVO

SecurityOCUP / Opus Genetics, Inc.
InstitutionRenaissance Technologies Llc
ManagerJames Simons
Latest Disclosed Ownership73,209 shares
Latest Disclosed Value $ 333,101
Renaissance Technologies Llc reports 42.04% decrease in ownership of OCUP / Opus Genetics, Inc.

On May 14, 2026 - Renaissance Technologies Llc filed a 13F-HR form disclosing ownership of 73,209 shares of Opus Genetics, Inc. (US:OCUP) valued at $333,101 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 12, 2026 disclosing 126,309 shares of Opus Genetics, Inc.. This represents a change in shares of -42.04% during the quarter. The current value of the position is $85,655 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-14 2026-03-31 13F OPUS GENETICS COM 67577R102 73,209 -53,100 -42.04 333 31.62 0.0005
2026-02-12 2025-12-31 13F OPUS GENETICS COM 67577R102 126,309 -47,500 -27.33 254 -11.54 0.0004
2025-11-13 2025-09-30 13F OPUS GENETICS COM 67577R102 173,809 20,500 13.37 287 98.61 0.0004
2025-08-13 2025-06-30 13F OPUS GENETICS COM 67577R102 153,309 29,600 23.93 144 19.01 0.0002
2025-05-14 2025-03-31 13F OPUS GENETICS COM 67577R102 123,709 -21,800 -14.98 121 -30.06 0.0002
2025-02-13 2024-12-31 13F OPUS GENETICS COM 67577R102 145,509 74,900 106.08 173 88.04 0.0003
2024-11-13 2024-09-30 13F OCUPHIRE PHARMA COM 67577R102 70,609 28,909 69.33 92 46.03 0.0001
2024-08-09 2024-06-30 13F OCUPHIRE PHARMA COM 67577R102 41,700 -93,600 -69.18 64 0.0001
2024-05-13 2024-03-31 13F OCUPHIRE PHARMA COM 67577R102 135,300 111,075 458.51 0 0.0004
2024-02-13 2023-12-31 13F OCUPHIRE PHARMA COM 67577R102 24,225 24,225 0 0.0001
2023-11-14 2023-09-30 13F OCUPHIRE PHARMA COM 67577R102 0 -99,600 -100.00 0 0.0000
2023-08-11 2023-06-30 13F OCUPHIRE PHARMA COM 67577R102 99,600 -90,369 -47.57 0 0.0006
2023-05-12 2023-03-31 13F OCUPHIRE PHARMA COM 67577R102 189,969 469 0.25 1 0.0009
2023-02-13 2022-12-31 13F OCUPHIRE PHARMA COM 67577R102 189,500 -17,401 -8.41 1 -100.00 0.0009
2022-11-14 2022-09-30 13F OCUPHIRE PHARMA COM 67577R102 206,901 8,711 4.40 416 9.19 0.0006
2022-08-12 2022-06-30 13F OCUPHIRE PHARMA COM 67577R102 198,190 198,190 381 0.0005
2022-05-13 2022-03-31 13F OCUPHIRE PHARMA COM 67577R102 0 -19,361 -100.00 0 -100.00
2022-02-11 2021-12-31 13F OCUPHIRE PHARMA COM 67577R102 19,361 19,361 72 0.0001
2021-11-12 2021-09-30 13F OCUPHIRE PHARMA COM 67577R102 0 -35,529 -100.00 0 -100.00
2021-08-13 2021-06-30 13F OCUPHIRE PHARMA COM 67577R102 35,529 -78,091 -68.73 188 -71.52 0.0002
2021-05-13 2021-03-31 13F OCUPHIRE PHARMA COM 67577R102 113,620 39,800 53.91 660 37.79 0.0008
2021-02-10 2020-12-31 13F OCUPHIRE PHARMA COM 67577R102 73,820 -159,482 -68.36 479 -1.24 0.0005
2020-11-13 2020-09-30 13F REXAHN PHARMACEUTICALS COM 761640309 233,302 24,001 11.47 485 -18.35 0.0005
2020-08-13 2020-06-30 13F REXAHN PHARMACEUTICALS COM 761640309 209,301 23,539 12.67 594 77.84 0.0005
2020-05-14 2020-03-31 13F REXAHN PHARMACEUTICALS COM 761640309 185,762 37,429 25.23 334 18.02 0.0003
2020-02-13 2019-12-31 13F REXAHN PHARMACEUTICALS COM 761640309 148,333 39,229 35.96 283 26.34 0.0002
2019-11-13 2019-09-30 13F REXAHN PHARMACEUTICALS COM 761640309 109,104 22,883 26.54 224 -49.66 0.0002
2019-08-12 2019-06-30 13F REXAHN PHARMACEUTICALS COM 761640309 86,221 -5,672,170 -98.50 445 -84.85 0.0004
2017-05-12 2017-03-31 13F REXAHN PHARMACEUTICALS COM 761640101 5,758,391 862,000 17.60 2,937 322.59 0.0041
2017-02-13 2016-12-31 13F REXAHN PHARMACEUTICALS COM 761640101 4,896,391 1,694,398 52.92 695 3.42 0.0011
2016-11-14 2016-09-30 13F REXAHN PHARMACEUTICALS COM 761640101 3,201,993 846,400 35.93 672 13.51 0.0012
2016-08-12 2016-06-30 13F REXAHN PHARMACEUTICALS COM 761640101 2,355,593 669,798 39.73 592 6.47 0.0011
2016-05-13 2016-03-31 13F REXAHN PHARMACEUTICALS COM 761640101 1,685,795 419,395 33.12 556 20.87 0.0011
2016-02-11 2015-12-31 13F REXAHN PHARMACEUTICALS COM 761640101 1,266,400 431,000 51.59 460 5.99 0.0010
2015-11-12 2015-09-30 13F REXAHN PHARMACEUTICALS COM 761640101 835,400 259,300 45.01 434 24.00 0.0010
2015-08-14 2015-06-30 13F REXAHN PHARMACEUTICALS COM 761640101 576,100 286,300 98.79 350 65.09 0.0008
2015-05-13 2015-03-31 13F REXAHN PHARMACEUTICALS COM 761640101 289,800 134,814 86.98 212 96.30 0.0005
2015-02-13 2014-12-31 13F REXAHN PHARMACEUTICALS COM 761640101 154,986 154,986 108 0.0003
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.