Sangamo Therapeutics, Inc.
US ˙ OTCPK ˙ US8006771062

SecuritySGMO / Sangamo Therapeutics, Inc.
InstitutionRenaissance Technologies Llc
ManagerJames Simons
Latest Disclosed Ownership3,836,665 shares
Latest Disclosed Value $ 947,273
Renaissance Technologies Llc reports 54.49% decrease in ownership of SGMO / Sangamo Therapeutics, Inc.

On May 14, 2026 - Renaissance Technologies Llc filed a 13F-HR form disclosing ownership of 3,836,665 shares of Sangamo Therapeutics, Inc. (US:SGMO) valued at $947,273 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 12, 2026 disclosing 8,430,323 shares of Sangamo Therapeutics, Inc.. This represents a change in shares of -54.49% during the quarter. The current value of the position is $681,392 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-14 2026-03-31 13F SANGAMO THERAPEUTICS COM 800677106 3,836,665 -4,593,658 -54.49 947 -73.25 0.0015
2026-02-12 2025-12-31 13F SANGAMO THERAPEUTICS COM 800677106 8,430,323 -1,752,140 -17.21 3,541 -48.37 0.0055
2025-11-13 2025-09-30 13F SANGAMO THERAPEUTICS COM 800677106 10,182,463 3,343,029 48.88 6,857 85.20 0.0091
2025-08-13 2025-06-30 13F SANGAMO THERAPEUTICS COM 800677106 6,839,434 3,671,327 115.88 3,702 78.24 0.0049
2025-05-14 2025-03-31 13F SANGAMO THERAPEUTICS COM 800677106 3,168,107 83,230 2.70 2,078 -33.98 0.0031
2025-02-13 2024-12-31 13F SANGAMO THERAPEUTICS COM 800677106 3,084,877 -1,767,900 -36.43 3,147 -25.13 0.0047
2024-11-13 2024-09-30 13F SANGAMO THERAPEUTICS COM 800677106 4,852,777 726,200 17.60 4,203 184.30 0.0063
2024-08-09 2024-06-30 13F SANGAMO THERAPEUTICS COM 800677106 4,126,577 1,528,600 58.84 1,479 147,700.00 0.0025
2024-05-13 2024-03-31 13F SANGAMO THERAPEUTICS COM 800677106 2,597,977 -547,901 -17.42 2 0.00 0.0027
2024-02-13 2023-12-31 13F SANGAMO THERAPEUTICS COM 800677106 3,145,878 780,124 32.98 2 0.00 0.0026
2023-11-14 2023-09-30 13F SANGAMO THERAPEUTICS COM 800677106 2,365,754 -701,742 -22.88 1 -66.67 0.0024
2023-08-11 2023-06-30 13F SANGAMO THERAPEUTICS COM 800677106 3,067,496 -165,299 -5.11 4 -40.00 0.0057
2023-05-12 2023-03-31 13F SANGAMO THERAPEUTICS COM 800677106 3,232,795 1,113,299 52.53 6 -16.67 0.0076
2023-02-13 2022-12-31 13F SANGAMO THERAPEUTICS COM 800677106 2,119,496 453,400 27.21 7 -99.93 0.0091
2022-11-14 2022-09-30 13F SANGAMO THERAPEUTICS COM 800677106 1,666,096 226,600 15.74 8,164 36.98 0.0115
2022-08-12 2022-06-30 13F SANGAMO THERAPEUTICS COM 800677106 1,439,496 676,400 88.64 5,960 34.42 0.0071
2022-05-13 2022-03-31 13F SANGAMO THERAPEUTICS COM 800677106 763,096 -87,600 -10.30 4,434 -30.50 0.0052
2022-02-11 2021-12-31 13F SANGAMO THERAPEUTICS COM 800677106 850,696 115,196 15.66 6,380 -3.73 0.0079
2021-11-12 2021-09-30 13F SANGAMO THERAPEUTICS COM 800677106 735,500 152,300 26.11 6,627 -5.07 0.0086
2021-08-13 2021-06-30 13F SANGAMO THERAPEUTICS COM 800677106 583,200 -196,600 -25.21 6,981 -28.55 0.0087
2021-05-13 2021-03-31 13F SANGAMO THERAPEUTICS COM 800677106 779,800 -512,800 -39.67 9,771 -51.56 0.0122
2021-02-10 2020-12-31 13F SANGAMO THERAPEUTICS COM 800677106 1,292,600 -32,891 -2.48 20,171 61.03 0.0219
2020-11-13 2020-09-30 13F SANGAMO THERAPEUTICS COM 800677106 1,325,491 1,325,491 12,526 0.0125
2020-02-12 2019-12-31 13F SANGAMO THERAPEUTICS COM 800677106 0 -67,000 -100.00 0 -100.00
2019-11-13 2019-09-30 13F SANGAMO THERAPEUTICS COM 800677106 67,000 -559,800 -89.31 606 -91.02 0.0005
2019-08-12 2019-06-30 13F SANGAMO THERAPEUTICS COM 800677106 626,800 -278,400 -30.76 6,751 -21.83 0.0059
2019-05-14 2019-03-31 13F SANGAMO THERAPEUTICS COM 800677106 905,200 905,200 44.42 8,636 27.92 0.0079
2018-05-14 2018-03-31 13F SANGAMO THERAPEUTICS COM 800677106 0 -23,800 -100.00 0 -100.00
2018-02-13 2017-12-31 13F SANGAMO THERAPEUTICS COM 800677106 23,800 23,800 390 0.0004
2017-05-12 2017-03-31 13F SANGAMO BIOSCIENCES COM 800677106 0 -321,819 -100.00 0 -100.00
2017-02-13 2016-12-31 13F SANGAMO BIOSCIENCES COM 800677106 321,819 -272,681 -45.87 982 -64.33 0.0016
2016-11-14 2016-09-30 13F SANGAMO BIOSCIENCES COM 800677106 594,500 480,300 420.58 2,753 316.49 0.0049
2016-08-12 2016-06-30 13F SANGAMO BIOSCIENCES COM 800677106 114,200 -389,864 -77.34 661 -78.33 0.0013
2016-05-13 2016-03-31 13F SANGAMO BIOSCIENCES COM 800677106 504,064 294,664 140.72 3,050 59.52 0.0058
2016-02-11 2015-12-31 13F SANGAMO BIOSCIENCES COM 800677106 209,400 -276,952 -56.94 1,912 -30.30 0.0042
2015-11-12 2015-09-30 13F SANGAMO BIOSCIENCES COM 800677106 486,352 378,655 351.59 2,743 129.73 0.0065
2015-08-14 2015-06-30 13F SANGAMO BIOSCIENCES COM 800677106 107,697 107,697 1,194 0.0027
2013-11-13 2013-09-30 13F SANGAMO BIOSCIENCES COM 800677106 0 -17,000 -100.00 0 -100.00
2013-08-12 2013-06-30 13F SANGAMO BIOSCIENCES COM 800677106 17,000 17,000 133 0.0003
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.