Tenaya Therapeutics, Inc.
US ˙ NasdaqGS ˙ US87990A1060

SecurityTNYA / Tenaya Therapeutics, Inc.
InstitutionVanguard Group Inc
Latest Disclosed Ownership8,560,108 shares
Latest Disclosed Value $ 6,094,797
Vanguard Group Inc reports 69.01% increase in ownership of TNYA / Tenaya Therapeutics, Inc.

On January 29, 2026 - Vanguard Group Inc filed a 13F-HR form disclosing ownership of 8,560,108 shares of Tenaya Therapeutics, Inc. (US:TNYA) valued at $6,090,517 USD as of December 31, 2025. The entity filed a previous 13F-HR on November 7, 2025 disclosing 5,064,857 shares of Tenaya Therapeutics, Inc.. This represents a change in shares of 69.01% during the quarter. The current value of the position is $6,232,615 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-01-29 2025-12-31 13F TENAYA THERAPEUTICS COM 87990A106 8,560,108 3,495,251 69.01 6,095 -25.73 0.0001
2025-11-07 2025-09-30 13F TENAYA THERAPEUTICS COM 87990A106 5,064,857 309,530 6.51 8,205 182.44 0.0001
2025-08-11 2025-06-30 13F TENAYA THERAPEUTICS COM 87990A106 4,755,327 673,295 16.49 2,906 24.89 0.0000
2025-05-09 2025-03-31 13F TENAYA THERAPEUTICS COM 87990A106 4,082,032 809,988 24.75 2,327 -50.29 0.0000
2025-02-11 2024-12-31 13F TENAYA THERAPEUTICS COM 87990A106 3,272,044 58,877 1.83 4,679 -24.54 0.0001
2024-11-13 2024-09-30 13F TENAYA THERAPEUTICS COM 87990A106 3,213,167 48,901 1.55 6,201 -36.78 0.0001
2024-08-13 2024-06-30 13F TENAYA THERAPEUTICS COM 87990A106 3,164,266 301,350 10.53 9,809 -34.49 0.0002
2024-05-10 2024-03-31 13F TENAYA THERAPEUTICS COM 87990A106 2,862,916 403,472 16.41 14,973 87.91 0.0003
2024-03-11 2023-12-31 13F/A-1 TENAYA THERAPEUTICS COM 87990A106 2,459,444 291,576 13.45 7,969 44.14 0.0002
2024-02-14 2023-12-31 13F TENAYA THERAPEUTICS COM 87990A106 2,459,444 291,576 7,969 0.0002
2023-12-18 2023-09-30 13F/A-1 TENAYA THERAPEUTICS COM 87990A106 2,167,868 168,489 8.43 5,528 -52.90 0.0001
2023-11-14 2023-09-30 13F TENAYA THERAPEUTICS COM 87990A106 2,167,868 168,489 5,528 0.0000
2023-08-14 2023-06-30 13F TENAYA THERAPEUTICS COM 87990A106 1,999,379 131,752 7.05 11,736 120.52 0.0003
2023-07-14 2023-03-31 13F/A-1 TENAYA THERAPEUTICS COM 87990A106 1,867,627 251,411 15.56 5,323 63.85 0.0001
2023-05-15 2023-03-31 13F TENAYA THERAPEUTICS COM 87990A106 1,867,627 251,411 5,323 0.0001
2023-02-10 2022-12-31 13F TENAYA THERAPEUTICS COM 87990A106 1,616,216 555,651 52.39 3,249 5.63 0.0001
2022-11-14 2022-09-30 13F TENAYA THERAPEUTICS COM 87990A106 1,060,565 -2,971 -0.28 3,075 -48.65 0.0001
2022-08-12 2022-06-30 13F TENAYA THERAPEUTICS COM 87990A106 1,063,536 -22,127 -2.04 5,988 -53.18 0.0002
2022-05-13 2022-03-31 13F TENAYA THERAPEUTICS COM 87990A106 1,085,663 528,845 94.98 12,789 21.20 0.0003
2022-02-14 2021-12-31 13F TENAYA THERAPEUTICS COM 87990A106 556,818 53,830 10.70 10,552 1.60 0.0002
2021-11-12 2021-09-30 13F TENAYA THERAPEUTICS COM 87990A106 502,988 502,988 10,386 0.0003
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.