HSTO Insider Trading - Histogen Inc.

Ações em Circulação	4,271,759 shares
Ações de Insider	12,138,101 shares

Pontuação de Sentimento de Insider

A Pontuação de Sentimento de Insider encontra as empresas que estão sendo compradas por insiders corporativos.

É o resultado de um modelo quantitativo sofisticado e multifatorial que identifica empresas com os mais altos níveis de acumulação por insiders. O modelo de pontuação usa uma combinação do número líquido de insiders comprando nos últimos 90 dias, o total de ações compradas como um percentual do float, e o total de ações possuídas por insiders. A escala varia de 0 a 100, com números mais altos indicando um maior nível de acumulação em relação aos seus pares, e 50 sendo a média.

Frequência de Atualização: Diariamente

Veja as Principais Escolhas dos Insiders, que fornece uma lista de empresas com a maior acumulação de insiders.

Veja as Ações de Maior Classificação

Pontuação de Sentimento dos Oficiais

A Pontuação de Sentimento de Officer encontra empresas que estão sendo compradas por Oficiais Corporativos.

Por definição, Oficiais Corporativos são Insiders Corporativos, mas, ao contrário de alguns outros Insiders (Acionistas de 10% e Membros do Conselho), os Oficiais trabalham para a empresa diariamente, e eles usam seu próprio dinheiro ao negociar. (Acionistas de 10% e Membros do Conselho muitas vezes são gestores de fundos que gerenciam o dinheiro de outras pessoas.) Como tal, as negociações de insiders feitas por Oficiais são muito mais significativas e devem ser tratadas apropriadamente.

Como a Pontuação de Sentimento dos Insiders, a Pontuação de Sentimento de Officer é o resultado de um modelo quantitativo sofisticado e multifatorial que identifica empresas com os mais altos níveis de acumulação por parte dos oficiais.

Frequência de Atualização: Diariamente

Veja as Principais Escolhas dos Insiders, que fornece uma lista de empresas com maior sentimento dos insiders.

Veja as Ações de Maior Classificação

Principais Métricas de Insider

Este cartão mostra como a empresa se classifica em várias métricas internas. O percentil mostra como esta empresa se compara a outras empresas nos mercados dos EUA. Classificações mais altas são indicativas de situações melhores.

Por exemplo, geralmente aceita-se que a compra interna é um indicador positivo, portanto, empresas com mais compras internas teriam classificações mais altas do que empresas com menos compras internas (ou até mesmo venda interna).

Número Líquido de Insiders Comprando (Classificação)

N/A

Número Líquido de Insiders Comprando é o número total de insiders comprando menos o número total de insiders vendendo nos últimos 90 dias. O percentil é mostrado aqui (varia de 0 a 100%).

Percentual do Float Comprado por Insiders (Classificação)

N/A

Percentual do Float Comprado por Insiders é o número total de ações compradas por insiders menos o número total de ações vendidas por insiders nos últimos 90 dias, dividido pelo total flutuante e multiplicado por 100.

Gráfico de Negociação de Insider

Histogen Inc. negociações de insiders são mostradas no seguinte gráfico. Insiders são oficiais, diretores ou investidores significativos em uma empresa. Em geral, é geralmente ilegal para insiders realizarem negociações em suas empresas com base em informações materiais, não públicas. Isso não significa que seja ilegal para eles fazerem quaisquer negociações em suas próprias empresas. No entanto, eles devem relatar todas as negociações à SEC através de um Formulário 4.

Roster de Insider e Métricas de Lucratividade

Esta tabela mostra a lista de insiders conhecidos, e é gerada automaticamente a partir de arquivamentos divulgados à SEC. Além dos nomes, título mais recente, e designação de diretor, oficial ou proprietário de 10%, fornecemos as últimas participações divulgadas. Adicionalmente, quando possível fornecemos o desempenho comercial histórico do insider. O desempenho comercial histórico é uma média ponderada do desempenho de transações reais de compra no mercado aberto feitas pelo insider. Para mais informações sobre como isso é calculado, assista este webinar no YouTube.

See our leaderboard of most profitable insider traders.

Insider	Lucro Médio (%)	Ações Possuídas	Ajuste de Divisão

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Acompanhar Históricos de Compras de Insiders - Análise de Lucro a Curto Prazo

Nesta seção, analisamos a lucratividade de cada compra de insider não planejada, feita no mercado aberto em HSTO / Histogen Inc.. Esta análise ajuda a entender se o insider gera consistentemente retornos anormais, e vale a pena ser seguido. Esta análise é para um ano após cada negociação, e os resultados são teóricos .

A tabela a seguir mostra as compras mais recentes no mercado aberto que não fizeram parte de um plano de negociação automática.

Data de Negociação	Insider	Reported Shares	Preço Reportado	Ações Ajustadas	Preço Ajustado	Base de Custo	Dias até Máx	Preço em Máx	Lucro Máximo ($)	Retorno Máximo (%)
2021-03-30	Pascoe Richard W	20,000	1.1400	1,000	22.8000	22,800	1	26	3,200	14.04
2020-12-03	Pascoe Richard W	10,000	1.2394	500	24.7880	12,394
2015-04-08	KISNER DANIEL L	4,000	5.7500	4,000	5.7500	23,000
2013-07-30	Aberdare GP III, L.L.C.	2,470	11.0000	2,470	11.0000	27,170
2013-07-30	Aberdare GP III, L.L.C.	104,952	11.0000	104,952	11.0000	1,154,472
2013-07-30	ADVENT VENTURE PARTNERS LLP	190,054	11.0000	190,054	11.0000	2,090,594
2013-07-30	HALE DAVID F	2,588	11.0000	2,588	11.0000	28,468
2013-07-30	COOPERATIVE GILDE HEALTHCARE II U.A.	165,525	11.0000	165,525	11.0000	1,820,775
2013-07-30	LACASSE LOUIS P	123,950	11.0000	123,950	11.0000	1,363,450

Preço Ajustado é o preço ajustado pelo desdobramento. Ações Ajustadas são as ações ajustadas pelo desdobramento.

Acompanhar Históricos de Vendas de Insiders - Análise de Perda a Curto Prazo

Nesta seção, analisamos a evitação de perda de curto prazo de cada venda de insider não planejada, feita no mercado aberto em HSTO / Histogen Inc.. Um padrão consistente de evitação de perdas pode sugerir que transações de venda futuras possam prever quedas no preço. Esta análise é para um ano após cada negociação, e os resultados são teóricos .

A tabela a seguir mostra as vendas mais recentes no mercado aberto que não fizeram parte de um plano de negociação automática.

Data de Negociação	Insider	Reported Shares	Preço Reportado	Ações Ajustadas	Preço Ajustado	Base de Custo	Dias até Mín
2013-07-30	Aberdare GP III, L.L.C.	14	11.0000	14	11.0000	154	282
2013-07-30	Aberdare GP III, L.L.C.	552	11.0000	552	11.0000	6,072
2013-07-30	ADVENT VENTURE PARTNERS LLP	535	11.0000	535	11.0000	5,885
2013-07-30	COOPERATIVE GILDE HEALTHCARE II U.A.	352	11.0000	352	11.0000	3,872

Preço Ajustado é o preço ajustado pelo desdobramento. Ações Ajustadas são as ações ajustadas pelo desdobramento.

Histórico de Transações

Clique no ícone de link para ver o histórico completo de transações. As transações relatadas como parte de um plano de negociação automática 10b5-1 terão um X na coluna marcada como 10b-5.

Arquivo Data	Data da Operação	Formulário	Insider	Ticker	Título de Segurança	Código	Direto	Preço de Exercício Preço Unitário	Preço por Unidade	Unidades Alteradas	Valor Alterado (1K)	Opções Restantes	Ações Restantes
2023-02-03		3	Spada Alfred P.	HSTO	Common Stock		I						1,235
2023-02-03		3	Spada Alfred P.	HSTO	Common Stock		D						979
2022-02-25	2022-02-24	4	Mento Steven J	HSTO	Stock Option (right to buy)	A - Award	D	0.24		151,642		151,642
2022-02-22	2022-02-17	4	Knudson Susan A.	HSTO	Stock Option (right to buy)	A - Award	D	0.24		169,800		169,800
2022-02-22	2022-02-17	4	Latterich Martin	HSTO	Stock Option (right to buy)	A - Award	D	0.24		134,900		134,900
2021-11-10	2021-11-08	4	Latterich Martin	HSTO	Restricted Stock Unit	A - Award	D			102,880		102,880
2021-11-10	2021-11-08	4	Mento Steven J	HSTO	Restricted Stock Unit	A - Award	D			228,395		228,395
2021-11-10	2021-11-08	4	Mento Steven J	HSTO	Stock Option (right to buy)	A - Award	D	0.73		377,830		377,830
2021-11-10	2021-11-08	4	Knudson Susan A.	HSTO	Restricted Stock Unit	A - Award	D			137,174		137,174
2021-09-03	2021-09-02	4	KISNER DANIEL L	HSTO	Stock Option (right to buy)	A - Award	D	0.82		20,000		20,000
2021-09-03	2021-09-02	4	Jackson Jonathan	HSTO	Stock Option (right to buy)	A - Award	D	0.82		20,000		20,000
2021-09-03	2021-09-02	4	Crean David Hugh	HSTO	Stock Option (right to buy)	A - Award	D	0.82		25,000		25,000
2021-09-03	2021-09-02	4	Mento Steven J	HSTO	Stock Option (right to buy)	A - Award	D	0.82		20,000		20,000
2021-09-03	2021-09-02	4	Satz Brian	HSTO	Stock Option (right to buy)	A - Award	D	0.82		20,000		20,000
2021-03-30	2021-03-30	4	Pascoe Richard W	HSTO	Common Stock	P - Purchase	D		1.1400	20,000	23		30,000
2021-03-26	2021-03-25	4	Fuhrmann Rochelle	HSTO	Stock Option (right to buy)	A - Award	D	1.27		30,000		30,000
2021-03-12	2021-03-10	4	Windham-Bannister Susan Richards	HSTO	Stock Option (right to buy)	A - Award	D	1.23		30,000		30,000
2021-01-15	2021-01-13	4	Pascoe Richard W	HSTO	Stock Option (right to buy)	A - Award	D	0.97		346,000		346,000
2021-01-15	2021-01-13	4	Naughton Gail K	HSTO	Stock Option (right to buy)	A - Award	D	0.97		95,000		95,000
2021-01-15	2021-01-13	4	Latterich Martin	HSTO	Stock Option (right to buy)	A - Award	D	0.97		90,000		90,000
2021-01-15	2021-01-13	4	Knudson Susan A.	HSTO	Stock Option (right to buy)	A - Award	D	0.97		112,000		112,000
2021-01-15	2021-01-13	4	Daniels Moya	HSTO	Stock Option (right to buy)	A - Award	D	0.97		100,000		100,000
2020-12-07	2020-12-03	4	Pascoe Richard W	HSTO	Common Stock	P - Purchase	D		1.2394	10,000	12		10,000
2020-10-19	2020-10-16	4	Daniels Moya	HSTO	Stock Option (right to buy)	A - Award	D	2.27		65,000		65,000
2020-10-09	2020-10-07	4	Satz Brian	HSTO	Stock Option (right to buy)	A - Award	D	1.89		20,000		20,000
2020-10-09	2020-10-07	4	Mento Steven J	HSTO	Stock Option (right to buy)	A - Award	D	1.89		20,000		20,000
2020-10-09	2020-10-07	4	Zhang Yizhuo	HSTO	Stock Option (right to buy)	A - Award	D	1.89		20,000		20,000
2020-10-09	2020-10-07	4	Crean David Hugh	HSTO	Stock Option (right to buy)	A - Award	D	1.89		20,000		20,000
2020-10-09	2020-10-07	4	KISNER DANIEL L	HSTO	Stock Option (right to buy)	A - Award	D	1.89		20,000		20,000
2020-10-09	2020-10-07	4	Jackson Jonathan	HSTO	Stock Option (right to buy)	A - Award	D	1.89		20,000		20,000
2020-10-09	2020-10-07	4	Chang Stephen	HSTO	Stock Option (right to buy)	A - Award	D	1.89		20,000		20,000
2020-05-29	2020-05-28	4	Knudson Susan A.	HSTO	Stock Option (right to buy)	A - Award	D	4.61		124,119		124,119
2020-05-28	2018-05-02	4	Crean David Hugh	HSTO	Stock Option (right to buy)	J - Other	D	3.84		35,855		35,855
2020-05-28	2017-10-25	4	Crean David Hugh	HSTO	Stock Option (right to buy)	J - Other	D	3.84		4,302		4,302
2020-05-28	2017-05-22	4	Crean David Hugh	HSTO	Stock Option (right to buy)	J - Other	D	3.70		17,210		17,210
2020-05-28	2020-05-26	4	Zhang Yizhuo	HSTO	Common Stock	J - Other	I			600,983			600,983
2020-05-28	2020-05-26	4	Chang Stephen	HSTO	Common Stock	J - Other	D			14,485			14,485
2020-05-28	2018-05-02	4	Chang Stephen	HSTO	Stock Option (right to buy)	J - Other	D	3.84		35,855		35,855
2020-05-28	2016-01-29	4	Chang Stephen	HSTO	Stock Option (right to buy)	J - Other	D	1.47		14,342		14,342
2020-05-28	2020-05-26	4	Jackson Jonathan	HSTO	Common Stock	J - Other	I			2,356,597			2,356,597
2020-05-28	2020-05-26	4	Latterich Martin	HSTO	Common Stock	J - Other	D			11,951			11,951
2020-05-28	2018-03-12	4	Latterich Martin	HSTO	Stock Option (right to buy)	J - Other	D	3.84		14,342		14,342
2020-05-28	2016-10-07	4	Latterich Martin	HSTO	Stock Option (right to buy)	J - Other	D	3.70		28,684		28,684
2020-05-28	2020-05-26	4	Satz Brian	HSTO	Common Stock	J - Other	D			1,434			1,434
2020-05-28	2018-05-02	4	Satz Brian	HSTO	Stock Option (right to buy)	J - Other	D	3.84		35,855		35,855
2020-05-28	2020-05-26	4	Naughton Gail K	HSTO	Common Stock	J - Other	I			426,526			426,526
2020-05-28	2012-05-12	4	Naughton Gail K	HSTO	Stock Option (right to buy)	J - Other	D	0.53		380,063		380,063
2020-05-28	2019-01-24	4	Pascoe Richard W	HSTO	Stock Option (right to buy)	J - Other	D	5.30		194,071		194,071
2020-05-28	2019-01-24	4	Pascoe Richard W	HSTO	Stock Option (right to buy)	J - Other	D	5.30		291,107		291,107
2020-05-27	2020-05-22	4	Mento Steven J	HSTO	Restricted Stock Units	M - Exercise	D			-65,000		0
2020-05-27	2020-05-22	4	Mento Steven J	HSTO	Common Stock	F - Taxes	D		0.5600	-31,428	-18		39,572
2020-05-27	2020-05-22	4	Mento Steven J	HSTO	Common Stock	M - Exercise	D			65,000			71,000
2020-05-27	2020-05-22	4	Spada Alfred P.	HSTO	Restricted Stock Units	M - Exercise	D			-31,343		0
2020-05-27	2020-05-22	4	Spada Alfred P.	HSTO	Common Stock	F - Taxes	D		0.5600	-12,960	-7		19,595
2020-05-27	2020-05-22	4	Spada Alfred P.	HSTO	Common Stock	M - Exercise	D			31,343			32,555
2020-05-27	2020-05-22	4	Marshall Keith W	HSTO	Restricted Stock Units	M - Exercise	D			-38,500		0
2020-05-27	2020-05-22	4	Marshall Keith W	HSTO	Common Stock	F - Taxes	D		0.5600	-18,615	-10		19,885
2020-05-27	2020-05-22	4	Marshall Keith W	HSTO	Common Stock	M - Exercise	D			38,500			38,500
2019-11-19	2019-11-18	4	Scott Kathleen D.	CNAT	Stock Option (Right to Buy)	A - Award	D	0.33		30,000		30,000
2019-08-01	2019-08-01	4	Marshall Keith W	CNAT	Restricted Stock Units	A - Award	D			385,000		385,000
2019-08-01	2019-08-01	4	Marshall Keith W	CNAT	Stock Option (Right to Buy)	D - Sale to Issuer	D	2.00		-175,000		0
2019-08-01	2019-08-01	4	Marshall Keith W	CNAT	Stock Option (Right to Buy)	D - Sale to Issuer	D	5.17		-70,000		0
2019-08-01	2019-08-01	4	Marshall Keith W	CNAT	Stock Option (Right to Buy)	D - Sale to Issuer	D	5.74		-525,000		0
2019-08-01	2019-08-01	4	Spada Alfred P.	CNAT	Restricted Stock Units	A - Award	D			313,436		313,436
2019-08-01	2019-08-01	4	Spada Alfred P.	CNAT	Stock Option (Right to Buy)	D - Sale to Issuer	D	2.00		-175,000		0
2019-08-01	2019-08-01	4	Spada Alfred P.	CNAT	Stock Option (Right to Buy)	D - Sale to Issuer	D	5.17		-70,000		0
2019-08-01	2019-08-01	4	Spada Alfred P.	CNAT	Stock Option (Right to Buy)	D - Sale to Issuer	D	4.21		-100,625		0
2019-08-01	2019-08-01	4	Spada Alfred P.	CNAT	Stock Option (Right to Buy)	D - Sale to Issuer	D	1.85		-21,875		0
2019-08-01	2019-08-01	4	Spada Alfred P.	CNAT	Stock Option (Right to Buy)	D - Sale to Issuer	D	1.85		-109,375		0
2019-08-01	2019-08-01	4	Spada Alfred P.	CNAT	Stock Option (Right to Buy)	D - Sale to Issuer	D	6.40		-100,000		0
2019-08-01	2019-08-01	4	Spada Alfred P.	CNAT	Stock Option (Right to Buy)	D - Sale to Issuer	D	9.45		-50,000		0
2019-08-01	2019-08-01	4	VANDERTIE MICHELLE L	CNAT	Restricted Stock Units	A - Award	D			86,375		86,375
2019-08-01	2019-08-01	4	VANDERTIE MICHELLE L	CNAT	Stock Option (Right to Buy)	D - Sale to Issuer	D	2.00		-50,000		0
2019-08-01	2019-08-01	4	VANDERTIE MICHELLE L	CNAT	Stock Option (Right to Buy)	D - Sale to Issuer	D	5.17		-16,000		0
2019-08-01	2019-08-01	4	VANDERTIE MICHELLE L	CNAT	Stock Option (Right to Buy)	D - Sale to Issuer	D	4.21		-23,000		0
2019-08-01	2019-08-01	4	VANDERTIE MICHELLE L	CNAT	Stock Option (Right to Buy)	D - Sale to Issuer	D	2.09		-20,000		0
2019-08-01	2019-08-01	4	VANDERTIE MICHELLE L	CNAT	Stock Option (Right to Buy)	D - Sale to Issuer	D	1.85		-3,750		0
2019-08-01	2019-08-01	4	VANDERTIE MICHELLE L	CNAT	Stock Option (Right to Buy)	D - Sale to Issuer	D	1.85		-15,000		0
2019-08-01	2019-08-01	4	VANDERTIE MICHELLE L	CNAT	Stock Option (Right to Buy)	D - Sale to Issuer	D	9.61		-15,000		0
2019-08-01	2019-08-01	4	VANDERTIE MICHELLE L	CNAT	Stock Option (Right to Buy)	D - Sale to Issuer	D	6.40		-15,000		0
2019-08-01	2019-08-01	4	VANDERTIE MICHELLE L	CNAT	Stock Option (Right to Buy)	D - Sale to Issuer	D	9.45		-15,000		0
2019-08-01	2019-08-01	4	Mento Steven J	CNAT	Restricted Stock Units	A - Award	D			650,000		650,000
2019-08-01	2019-08-01	4	Mento Steven J	CNAT	Stock Option (Right to Buy)	D - Sale to Issuer	D	2.00		-350,000		0
2019-08-01	2019-08-01	4	Mento Steven J	CNAT	Stock Option (Right to Buy)	D - Sale to Issuer	D	5.17		-120,000		0
2019-08-01	2019-08-01	4	Mento Steven J	CNAT	Stock Option (Right to Buy)	D - Sale to Issuer	D	4.21		-172,500		0
2019-08-01	2019-08-01	4	Mento Steven J	CNAT	Stock Option (Right to Buy)	D - Sale to Issuer	D	1.85		-37,500		0
2019-08-01	2019-08-01	4	Mento Steven J	CNAT	Stock Option (Right to Buy)	D - Sale to Issuer	D	1.85		-20,000		0
2019-08-01	2019-08-01	4	Mento Steven J	CNAT	Stock Option (Right to Buy)	D - Sale to Issuer	D	6.40		-50,000		0
2019-08-01	2019-08-01	4	Mento Steven J	CNAT	Stock Option (Right to Buy)	D - Sale to Issuer	D	6.40		-150,000		0
2019-08-01	2019-08-01	4	Mento Steven J	CNAT	Stock Option (Right to Buy)	D - Sale to Issuer	D	9.45		-400,000		0
2019-07-01	2019-06-27	4	HALE DAVID F	CNAT	Stock Option (Right to Buy)	A - Award	D	0.29		45,000		45,000
2019-07-01	2019-06-27	4	KISNER DANIEL L	CNAT	Stock Option (Right to Buy)	A - Award	D	0.29		20,000		20,000
2019-07-01	2019-06-27	4	Klassen Preston	CNAT	Stock Option (Right to Buy)	A - Award	D	0.29		20,000		20,000
2019-07-01	2019-06-27	4	LARUE WILLIAM R	CNAT	Stock Option (Right to Buy)	A - Award	D	0.29		20,000		20,000
2019-07-01	2019-06-27	4	Van Wart Harold	CNAT	Stock Option (Right to Buy)	A - Award	D	0.29		20,000		20,000
2019-02-11	2019-02-07	4	RIPLEY DANIEL L.	CNAT	Stock Option (Right to Buy)	A - Award	D	2.00		100,000		100,000
2019-02-11	2018-11-14	4	RIPLEY DANIEL L. See footnote.	CNAT	Common Stock	A - Award	I		3.1500	1,861	6		32,431
2019-02-11	2018-05-14	4	RIPLEY DANIEL L. See footnote.	CNAT	Common Stock	A - Award	I		3.3100	1,290	4		30,570
2019-02-11	2019-02-07	4	Marshall Keith W	CNAT	Stock Option (Right to Buy)	A - Award	D	2.00		175,000		175,000
2019-02-11	2019-02-07	4	Smith Edward F III	CNAT	Stock Option (Right to Buy)	A - Award	D	2.00		100,000		100,000
2019-02-11	2018-11-14	4	Smith Edward F III	CNAT	Common Stock	A - Award	D		3.1500	1,724	5		10,875
2019-02-11	2018-05-14	4	Smith Edward F III	CNAT	Common Stock	A - Award	D		3.3100	4,690	16		9,151
2019-02-11	2019-02-07	4	Spada Alfred P.	CNAT	Stock Option (Right to Buy)	A - Award	D	2.00		175,000		175,000
2019-02-11	2019-02-07	4	VANDERTIE MICHELLE L	CNAT	Stock Option (Right to Buy)	A - Award	D	2.00		50,000		50,000
2019-02-11	2019-02-07	4	Mento Steven J	CNAT	Stock Option (Right to Buy)	A - Award	D	2.00		350,000		350,000
2019-02-11	2019-02-07	4	Hagerty David T	CNAT	Stock Option (Right to Buy)	A - Award	D	2.00		175,000		175,000
2018-06-25	2018-06-21	4	KISNER DANIEL L	CNAT	Stock Option (Right to Buy)	A - Award	D	4.99		20,000		20,000
2018-06-25	2018-06-21	4	Klassen Preston	CNAT	Stock Option (Right to Buy)	A - Award	D	4.99		20,000		20,000
2018-06-25	2018-06-21	4	LARUE WILLIAM R	CNAT	Stock Option (Right to Buy)	A - Award	D	4.99		20,000		20,000
2018-06-25	2018-06-21	4	Scopa James Paul	CNAT	Stock Option (Right to Buy)	A - Award	D	4.99		20,000		20,000
2018-06-25	2018-06-21	4	Van Wart Harold	CNAT	Stock Option (Right to Buy)	A - Award	D	4.99		20,000		20,000
2018-06-25	2018-06-21	4	HALE DAVID F	CNAT	Stock Option (Right to Buy)	A - Award	D	4.99		45,000		45,000
2018-05-07	2018-05-04	4	Mento Steven J	CNAT	Stock Option (Right to Buy)	M - Exercise	D	0.99		-60,000		147,070
2018-05-07	2018-05-04	4	Mento Steven J	CNAT	Common Stock	M - Exercise	D		0.9900	60,000	59		60,000
2018-03-01	2018-02-27	4	Spada Alfred P.	CNAT	Stock Option (Right to Buy)	M - Exercise	D	1.24		-12,121		0
2018-03-01	2018-02-27	4	Spada Alfred P.	CNAT	Common Stock	M - Exercise	D		1.2400	12,121	15		12,121
2018-02-05	2017-05-30	5	VANDERTIE MICHELLE L See footnote.	CNAT	Common Stock	G - Gift	I			-2,165			2,813
2018-02-05	2018-02-04	4	Mento Steven J	CNAT	Stock Option (Right to Buy)	A - Award	D	5.17		120,000		120,000
2018-02-05	2018-02-04	4	Hagerty David T	CNAT	Stock Option (Right to Buy)	A - Award	D	5.17		70,000		70,000
2018-02-05	2018-02-04	4	Marshall Keith W	CNAT	Stock Option (Right to Buy)	A - Award	D	5.17		70,000		70,000
2018-02-05	2018-02-04	4	RIPLEY DANIEL L.	CNAT	Stock Option (Right to Buy)	A - Award	D	5.17		40,000		40,000
2018-02-05	2017-11-14	4	RIPLEY DANIEL L. See footnote.	CNAT	Common Stock	A - Award	I		3.4800	818	3		29,280
2018-02-05	2017-05-12	4	RIPLEY DANIEL L. See footnote.	CNAT	Common Stock	A - Award	I		1.7000	761	1		28,462
2018-02-05	2018-02-04	4	Smith Edward F III	CNAT	Stock Option (Right to Buy)	A - Award	D	5.17		40,000		40,000
2018-02-05	2017-11-14	4	Smith Edward F III	CNAT	Common Stock	A - Award	D		3.4800	4,461	16		4,461
2018-02-05	2018-02-04	4	Spada Alfred P.	CNAT	Stock Option (Right to Buy)	A - Award	D	5.17		70,000		70,000
2018-02-05	2018-02-04	4	VANDERTIE MICHELLE L	CNAT	Stock Option (Right to Buy)	A - Award	D	5.17		16,000		16,000
2017-09-01	2017-08-31	4	Marshall Keith W	CNAT	Stock Option (Right to Buy)	A - Award	D	5.74		525,000		525,000
2017-06-26	2017-06-22	4	Van Wart Harold	CNAT	Stock Option (Right to Buy)	A - Award	D	4.96		20,000		20,000
2017-06-26	2017-06-22	4	KISNER DANIEL L	CNAT	Stock Option (Right to Buy)	A - Award	D	4.96		20,000		20,000
2017-06-26	2017-06-22	4	Klassen Preston	CNAT	Stock Option (Right to Buy)	A - Award	D	4.96		20,000		20,000
2017-06-26	2017-06-22	4	Scopa James Paul	CNAT	Stock Option (Right to Buy)	A - Award	D	4.96		20,000		20,000
2017-06-26	2017-06-22	4	HALE DAVID F	CNAT	Stock Option (Right to Buy)	A - Award	D	4.96		45,000		45,000
2017-04-07		3	VANDERTIE MICHELLE L See footnote.	CNAT	Common Stock		I						9,956
2017-04-07		3	VANDERTIE MICHELLE L See footnote.	CNAT	Common Stock		I						9,956
2017-02-07	2017-02-06	4	LARUE WILLIAM R	CNAT	Stock Option (Right to Buy)	A - Award	D	5.09		30,000		30,000
2017-02-02		3	RIPLEY DANIEL L. See footnote.	CNAT	Common Stock		I						55,402
2017-02-02		3	RIPLEY DANIEL L. See footnote.	CNAT	Common Stock		I						55,402
2017-02-02	2017-01-26	4	RIPLEY DANIEL L.	CNAT	Stock Option (Right to Buy)	A - Award	D	4.21		73,000		73,000
2017-02-01	2017-01-26	4	Mento Steven J	CNAT	Stock Option (Right to Buy)	A - Award	D	4.21		172,500		172,500
2017-02-01	2017-01-26	4	Cashion Charles	CNAT	Stock Option (Right to Buy)	A - Award	D	4.21		57,500		57,500
2017-02-01	2017-01-26	4	Hagerty David T	CNAT	Stock Option (Right to Buy)	A - Award	D	4.21		100,625		100,625
2017-02-01	2017-01-26	4	Spada Alfred P.	CNAT	Stock Option (Right to Buy)	A - Award	D	4.21		100,625		100,625
2017-02-01	2017-01-26	4	Smith Edward F III	CNAT	Stock Option (Right to Buy)	A - Award	D	4.21		57,500		57,500
2017-01-11	2017-01-09	4	Cashion Charles	CNAT	Stock Option (Right to Buy)	M - Exercise	D	0.99		-42,424		0
2017-01-11	2017-01-09	4	Cashion Charles	CNAT	Common Stock	M - Exercise	D		0.9900	42,424	42		42,424
2016-12-30	2014-02-19	4/A	KISNER DANIEL L	CNAT	Common Stock	J - Other	I			3,145			3,145
2016-12-30	2016-12-28	4	KISNER DANIEL L	CNAT	Common Stock	J - Other	I			2,310			5,455
2016-12-22	2016-12-20	4	Mento Steven J	CNAT	Stock Option (Right to Buy)	M - Exercise	D	0.99		-5,051		207,070
2016-12-22	2016-12-20	4	Mento Steven J	CNAT	Stock Option (Right to Buy)	M - Exercise	D	1.24		-36,363		0
2016-12-22	2016-12-20	4	Mento Steven J	CNAT	Common Stock	M - Exercise	D		0.9900	5,051	5		41,414
2016-12-22	2016-12-20	4	Mento Steven J	CNAT	Common Stock	M - Exercise	D		1.2400	36,363	45		36,363
2016-10-31	2016-10-27	4	Van Wart Harold	CNAT	Stock Option (Right to Buy)	M - Exercise	D	0.25		-18,181		0
2016-10-31	2016-10-27	4	Van Wart Harold	CNAT	Common Stock	M - Exercise	D		0.2500	18,181	5		18,181
2016-06-27	2016-06-23	4	Malik Shahzad	CNAT	Stock Option (Right to Buy)	A - Award	D	2.13		20,000		20,000
2016-06-24	2016-06-23	4	HALE DAVID F	CNAT	Stock Option (Right to Buy)	A - Award	D	2.13		45,000		45,000
2016-06-24	2016-06-23	4	KISNER DANIEL L	CNAT	Stock Option (Right to Buy)	A - Award	D	2.13		20,000		20,000
2016-06-24	2016-06-23	4	Scopa James Paul	CNAT	Stock Option (Right to Buy)	A - Award	D	2.13		20,000		20,000
2016-06-24	2016-06-23	4	Klassen Preston	CNAT	Stock Option (Right to Buy)	A - Award	D	2.13		20,000		20,000
2016-06-24	2016-06-23	4	Van Wart Harold	CNAT	Stock Option (Right to Buy)	A - Award	D	2.13		20,000		20,000
2016-04-04	2016-04-01	4	Smith Edward F III	CNAT	Stock Option (Right to Buy)	A - Award	D	2.53		100,000		100,000
2016-02-08	2016-02-04	4	Mento Steven J	CNAT	Stock Option (Right to Buy)	A - Award	D	1.85		37,500		37,500
2016-02-08	2016-02-04	4	Mento Steven J	CNAT	Stock Option (Right to Buy)	A - Award	D	1.85		187,500		187,500
2016-02-08	2016-02-04	4	Cashion Charles	CNAT	Stock Option (Right to Buy)	A - Award	D	1.85		12,500		12,500
2016-02-08	2016-02-04	4	Cashion Charles	CNAT	Stock Option (Right to Buy)	A - Award	D	1.85		50,000		50,000
2016-02-08	2016-02-04	4	Hagerty David T	CNAT	Stock Option (Right to Buy)	A - Award	D	1.85		21,875		21,875
2016-02-08	2016-02-04	4	Hagerty David T	CNAT	Stock Option (Right to Buy)	A - Award	D	1.85		109,375		109,375
2016-02-08	2016-02-04	4	Spada Alfred P.	CNAT	Stock Option (Right to Buy)	A - Award	D	1.85		21,875		21,875
2016-02-08	2016-02-04	4	Spada Alfred P.	CNAT	Stock Option (Right to Buy)	A - Award	D	1.85		109,375		109,375
2015-06-15	2015-06-11	4	HALE DAVID F	CNAT	Stock Option (Right to Buy)	A - Award	D	5.52		35,000		35,000
2015-06-15	2015-06-11	4	KISNER DANIEL L	CNAT	Stock Option (Right to Buy)	A - Award	D	5.52		15,000		15,000
2015-06-15	2015-06-11	4	LACASSE LOUIS P	CNAT	Stock Option (Right to Buy)	A - Award	D	5.52		15,000		15,000
2015-06-15	2015-06-11	4	Malik Shahzad	CNAT	Stock Option (Right to Buy)	A - Award	D	5.52		15,000		15,000
2015-06-15	2015-06-11	4	Scopa James Paul	CNAT	Stock Option (Right to Buy)	A - Award	D	5.52		15,000		15,000
2015-06-15	2015-06-11	4	Klassen Preston	CNAT	Stock Option (Right to Buy)	A - Award	D	5.52		15,000		15,000
2015-06-15	2015-06-11	4	Van Wart Harold	CNAT	Stock Option (Right to Buy)	A - Award	D	5.52		15,000		15,000
2015-04-10	2015-04-08	4	KISNER DANIEL L	CNAT	Common Stock	P - Purchase	D		5.7500	4,000	23		7,145
2015-02-25	2015-02-23	4	Cashion Charles	CNAT	Stock Option (Right to Buy)	A - Award	D	6.40		50,000		50,000
2015-02-25	2015-02-23	4	Mento Steven J	CNAT	Stock Option (Right to Buy)	A - Award	D	6.40		50,000		50,000
2015-02-25	2015-02-23	4	Mento Steven J	CNAT	Stock Option (Right to Buy)	A - Award	D	6.40		150,000		150,000
2015-02-25	2015-02-23	4	Spada Alfred P.	CNAT	Stock Option (Right to Buy)	A - Award	D	6.40		100,000		100,000
2015-02-06	2014-04-02	5	Cashion Charles See footnote.	CNAT	Common Stock	G - Gift	I			-5,000			144,738
2014-10-03	2014-10-01	4	Hagerty David T	CNAT	Stock Option (Right to Buy)	A - Award	D	5.92		175,000		175,000
2014-06-23	2014-06-19	4	HALE DAVID F	CNAT	Stock Option (Right to Buy)	A - Award	D	7.97		35,000		35,000
2014-06-23	2014-06-19	4	LACASSE LOUIS P	CNAT	Stock Option (Right to Buy)	A - Award	D	7.97		15,000		15,000
2014-06-23	2014-06-19	4	Malik Shahzad	CNAT	Stock Option (Right to Buy)	A - Award	D	7.97		15,000		15,000
2014-06-23	2014-06-19	4	Scopa James Paul	CNAT	Stock Option (Right to Buy)	A - Award	D	7.97		15,000		15,000
2014-06-23	2014-06-19	4	Van Wart Harold	CNAT	Stock Option (Right to Buy)	A - Award	D	7.97		15,000		15,000
2014-02-25	2014-02-19	4	KISNER DANIEL L	CNAT	Common Stock	J - Other	D			3,145			3,145
2014-02-25	2014-02-19	4	Aberdare GP III, L.L.C. By Aberdare GP III, L.L.C.	CNAT	Common Stock	J - Other	I			-36,634			0
2014-02-25	2014-02-19	4	Aberdare GP III, L.L.C. By Aberdare GP III, L.L.C.	CNAT	Common Stock	J - Other	I			36,634			36,634
2014-02-25	2014-02-19	4	Aberdare GP III, L.L.C. By Aberdare Partners III, L.P.	CNAT	Common Stock	J - Other	I			-30,216			22,203
2014-02-25	2014-02-19	4	Aberdare GP III, L.L.C. By Aberdare Ventures III, L.P.	CNAT	Common Stock	J - Other	I			-1,283,589			943,355
2014-02-25	2014-02-19	4	KLINGENSTEIN PAUL H By Klingenstein-Bole 2003 Irrevocable Children's Trust	CNAT	Common Stock	J - Other	I			8,731			8,731
2014-02-25	2014-02-19	4	KLINGENSTEIN PAUL H	CNAT	Common Stock	J - Other	D			20,322			20,322
2014-02-25	2014-02-19	4	KLINGENSTEIN PAUL H By Aberdare GP III, L.L.C.	CNAT	Common Stock	J - Other	I			-36,634			0
2014-02-25	2014-02-19	4	KLINGENSTEIN PAUL H By Aberdare GP III, L.L.C.	CNAT	Common Stock	J - Other	I			36,634			36,634
2014-02-25	2014-02-19	4	KLINGENSTEIN PAUL H By Aberdare Partners III, L.P.	CNAT	Common Stock	J - Other	I			-30,216			22,203
2014-02-25	2014-02-19	4	KLINGENSTEIN PAUL H By Aberdare Ventures III, L.P.	CNAT	Common Stock	J - Other	I			-1,283,589			943,355
2014-02-11	2014-02-07	4	KISNER DANIEL L	CNAT	Stock Option (Right to Buy)	A - Award	D	9.45		30,000		30,000
2014-02-11	2014-02-07	4	Mento Steven J	CNAT	Stock Option (Right to Buy)	A - Award	D	9.45		400,000		400,000
2014-02-11	2014-02-07	4	Cashion Charles	CNAT	Stock Option (Right to Buy)	A - Award	D	9.45		50,000		50,000
2014-02-11	2014-02-07	4	Klassen Preston	CNAT	Stock Option (Right to Buy)	A - Award	D	9.45		30,000		30,000
2014-02-11	2014-02-07	4	Spada Alfred P.	CNAT	Stock Option (Right to Buy)	A - Award	D	9.45		50,000		50,000
2014-02-11	2014-02-07	4	BURGESS GARY C.	CNAT	Stock Option (Right to Buy)	A - Award	D	9.45		50,000		50,000
2014-01-10	2014-01-08	4	HALE DAVID F	CNAT	Stock Option (Right to Buy)	M - Exercise	D	0.99		-12,121		0
2014-01-10	2014-01-08	4	HALE DAVID F	CNAT	Common Stock	M - Exercise	D		0.9900	12,121	12		24,242
2013-09-27	2013-09-26	4	HALE DAVID F	CNAT	Stock Option (Right to Buy)	M - Exercise	D	2.31		-12,121		0
2013-09-27	2013-09-26	4	HALE DAVID F	CNAT	Common Stock	M - Exercise	D		2.3100	12,121	28		12,121
2013-08-01	2013-07-30	4	Scopa James Paul	CNAT	Stock Option (Right to Buy)	A - Award	D	11.00		30,000		30,000
2013-08-01	2013-07-30	4	Scopa James Paul	CNAT	Warrant to Purchase Common Stock (Right to Buy)	C - Conversion	I	7.43		32,220		32,220
2013-08-01	2013-07-30	4	Scopa James Paul	CNAT	Warrant to Purchase Series B Preferred Stock (Right to Buy)	C - Conversion	I	0.90		-265,837		0
2013-08-01	2013-07-30	4	Scopa James Paul	CNAT	Series B Convertible Preferred Stock	C - Conversion	I			-8,333,334		0
2013-08-01	2013-07-30	4	Scopa James Paul	CNAT	Common Stock	P - Purchase	I		11.0000	165,265	1,818		1,192,080
2013-08-01	2013-07-30	4	Scopa James Paul	CNAT	Common Stock	J - Other	I		11.0000	16,716	184		1,026,815
2013-08-01	2013-07-30	4	Scopa James Paul	CNAT	Common Stock	C - Conversion	I			1,010,099			1,010,099
2013-08-01	2013-07-30	4	ADVENT VENTURE PARTNERS LLP See footnotes	CNAT	Warrants to Purchase Shares of Series A Preferred Stock	X - Other	I			-577,599		0
2013-08-01	2013-07-30	4	ADVENT VENTURE PARTNERS LLP See footnotes	CNAT	Series B Preferred Stock	C - Conversion	I			-5,576,786		0
2013-08-01	2013-07-30	4	ADVENT VENTURE PARTNERS LLP See footnotes	CNAT	Series A Preferred Stock	C - Conversion	I			-10,000,000		0
2013-08-01	2013-07-30	4	ADVENT VENTURE PARTNERS LLP See footnotes	CNAT	Common Stock	P - Purchase	I		11.0000	190,054	2,091		2,166,836
2013-08-01	2013-07-30	4	ADVENT VENTURE PARTNERS LLP	CNAT	Common Stock	J - Other	I		11.0000	19,223	211		1,976,782
2013-08-01	2013-07-30	4	ADVENT VENTURE PARTNERS LLP	CNAT	Common Stock	S - Sale	I		11.0000	-535	-6		1,957,559
2013-08-01	2013-07-30	4	ADVENT VENTURE PARTNERS LLP	CNAT	Common Stock	X - Other	I		0.0825	70,003	6		1,958,094
2013-08-01	2013-07-30	4	ADVENT VENTURE PARTNERS LLP See footnotes	CNAT	Common Stock	C - Conversion	I			1,888,091			1,888,091
2013-08-01	2013-07-30	4	HALE DAVID F	CNAT	Stock Option (Right to Buy)	A - Award	D	11.00		50,000		50,000
2013-08-01	2013-07-30	4	HALE DAVID F	CNAT	Series A Preferred Stock	C - Conversion	I			-162,356		0
2013-08-01	2013-07-30	4	HALE DAVID F	CNAT	Common Stock	P - Purchase	I		11.0000	2,588	28		143,739
2013-08-01	2013-07-30	4	HALE DAVID F	CNAT	Common Stock	J - Other	I		11.0000	261	3		141,151
2013-08-01	2013-07-30	4	HALE DAVID F	CNAT	Common Stock	C - Conversion	I			19,679			140,890
2013-08-01	2013-07-30	4	LACASSE LOUIS P	CNAT	Stock Option (Right to Buy)	A - Award	D	11.00		30,000		30,000
2013-08-01	2013-07-30	4	LACASSE LOUIS P	CNAT	Series B Preferred Stock	C - Conversion	I			-5,555,556		0
2013-08-01	2013-07-30	4	LACASSE LOUIS P	CNAT	Common Stock	P - Purchase	I		11.0000	123,950	1,363		809,887
2013-08-01	2013-07-30	4	LACASSE LOUIS P	CNAT	Common Stock	J - Other	I		11.0000	12,537	138		685,937
2013-08-01	2013-07-30	4	LACASSE LOUIS P	CNAT	Common Stock	C - Conversion	I			673,400			673,400
2013-08-01	2013-07-30	4	Malik Shahzad	CNAT	Stock Option (Right to Buy)	A - Award	D	11.00		30,000		30,000
2013-08-01	2013-07-30	4	Malik Shahzad See footnotes	CNAT	Warrants to Purchase Shares of Series A Preferred Stock	X - Other	I			-577,599		0
2013-08-01	2013-07-30	4	Malik Shahzad See footnotes	CNAT	Series B Preferred Stock	C - Conversion	I			-5,576,786		0
2013-08-01	2013-07-30	4	Malik Shahzad See footnotes	CNAT	Series A Preferred Stock	C - Conversion	I			-10,000,000		0
2013-08-01	2013-07-30	4	Malik Shahzad	CNAT	Common Stock	P - Purchase	I		11.0000	190,054	2,091		2,166,836
2013-08-01	2013-07-30	4	Malik Shahzad	CNAT	Common Stock	J - Other	I		11.0000	19,223	211		1,976,782
2013-08-01	2013-07-30	4	Malik Shahzad	CNAT	Common Stock	S - Sale	I		11.0000	-535	-6		1,957,559
2013-08-01	2013-07-30	4	Malik Shahzad	CNAT	Common Stock	X - Other	I		0.0825	70,003	6		1,958,094
2013-08-01	2013-07-30	4	Malik Shahzad See footnotes	CNAT	Common Stock	C - Conversion	I			1,888,091			1,888,091
2013-08-01	2013-07-30	4	Mento Steven J	CNAT	Series A Preferred Stock	C - Conversion	I			-786,417		0
2013-08-01	2013-07-30	4	Mento Steven J	CNAT	Common Stock	P - Purchase	I		11.0000	13,800	152		385,669
2013-08-01	2013-07-30	4	Mento Steven J	CNAT	Common Stock	J - Other	I		11.0000	1,395	15		371,869
2013-08-01	2013-07-30	4	Mento Steven J	CNAT	Common Stock	C - Conversion	I			95,323			370,474
2013-08-01	2013-07-30	4	Cashion Charles	CNAT	Series A Preferred Stock	C - Conversion	I			-355,352		0
2013-08-01	2013-07-30	4	Cashion Charles	CNAT	Common Stock	C - Conversion	I			43,072			149,738
2013-08-01	2013-07-30	4	Perret Marc Olivier	CNAT	Stock Option (Right to Buy)	A - Award	D	11.00		30,000		30,000
2013-08-01	2013-07-30	4	Perret Marc Olivier See footnotes	CNAT	Warrants to Purchase Shares of Series A Preferred Stock	X - Other	I			-385,070		0
2013-08-01	2013-07-30	4	Perret Marc Olivier See footnotes	CNAT	Series B Preferred Stock	C - Conversion	I			-3,717,861		0
2013-08-01	2013-07-30	4	Perret Marc Olivier See footnotes	CNAT	Series A Preferred Stock	C - Conversion	I			-6,666,668		0
2013-08-01	2013-07-30	4	Perret Marc Olivier See footnotes	CNAT	Common Stock	P - Purchase	I		11.0000	165,525	1,821		1,487,320
2013-08-01	2013-07-30	4	Perret Marc Olivier See footnotes	CNAT	Common Stock	J - Other	I		11.0000	16,742	184		1,321,795
2013-08-01	2013-07-30	4	Perret Marc Olivier See footnotes	CNAT	Common Stock	S - Sale	I		11.0000	-352	-4		1,305,053
2013-08-01	2013-07-30	4	Perret Marc Olivier See footnotes	CNAT	Common Stock	X - Other	I			46,675			1,305,405
2013-08-01	2013-07-30	4	Perret Marc Olivier See footnotes	CNAT	Common Stock	C - Conversion	I			1,258,730			1,258,730
2013-08-01	2013-07-30	4	EVNIN LUKE	CNAT	Warrant to Purchase Common Stock (Right to Buy)	C - Conversion	I	7.43		32,220		32,220
2013-08-01	2013-07-30	4	EVNIN LUKE	CNAT	Warrant to Purchase Series B Preferred Stock (Right to Buy)	C - Conversion	I	0.90		-265,837		0
2013-08-01	2013-07-30	4	EVNIN LUKE	CNAT	Series B Convertible Preferred Stock	C - Conversion	I			-8,333,334		0
2013-08-01	2013-07-30	4	EVNIN LUKE	CNAT	Common Stock	P - Purchase	I		11.0000	165,265	1,818		1,192,080
2013-08-01	2013-07-30	4	EVNIN LUKE	CNAT	Common Stock	J - Other	I		11.0000	16,716	184		1,026,815
2013-08-01	2013-07-30	4	EVNIN LUKE	CNAT	Common Stock	C - Conversion	I			1,010,099			1,010,099
2013-08-01	2013-07-30	4	MPM BioVentures IV QP LP	CNAT	Warrant to Purchase Common Stock (Right to Buy)	C - Conversion	I	7.43		32,220		32,220
2013-08-01	2013-07-30	4	MPM BioVentures IV QP LP	CNAT	Warrant to Purchase Series B Preferred Stock (Right to Buy)	C - Conversion	I	0.90		-265,837		0
2013-08-01	2013-07-30	4	MPM BioVentures IV QP LP	CNAT	Series B Convertible Preferred Stock	C - Conversion	I			-8,333,334		0
2013-08-01	2013-07-30	4	MPM BioVentures IV QP LP	CNAT	Common Stock	P - Purchase	I		11.0000	165,265	1,818		1,192,080
2013-08-01	2013-07-30	4	MPM BioVentures IV QP LP	CNAT	Common Stock	J - Other	I		11.0000	16,716	184		1,026,815
2013-08-01	2013-07-30	4	MPM BioVentures IV QP LP	CNAT	Common Stock	C - Conversion	I			1,010,099			1,010,099
2013-08-01	2013-07-30	4	Spada Alfred P.	CNAT	Series A Preferred Stock	C - Conversion	I			-363,927		0
2013-08-01	2013-07-30	4	Spada Alfred P.	CNAT	Common Stock	C - Conversion	I			44,112			235,021
2013-08-01	2013-07-30	4	Van Wart Harold	CNAT	Stock Option (Right to Buy)	A - Award	D	11.00		30,000		30,000
2013-08-01	2013-07-30	4	COOPERATIVE GILDE HEALTHCARE II U.A.	CNAT	Warrants to Purchase Shares of Series A Preferred Stock	X - Other	D			-385,070		0
2013-08-01	2013-07-30	4	COOPERATIVE GILDE HEALTHCARE II U.A.	CNAT	Series B Preferred Stock	C - Conversion	D			-3,717,861		0
2013-08-01	2013-07-30	4	COOPERATIVE GILDE HEALTHCARE II U.A.	CNAT	Series A Preferred Stock	C - Conversion	D			-6,666,668		0
2013-08-01	2013-07-30	4	COOPERATIVE GILDE HEALTHCARE II U.A.	CNAT	Common Stock	P - Purchase	D		11.0000	165,525	1,821		1,487,320
2013-08-01	2013-07-30	4	COOPERATIVE GILDE HEALTHCARE II U.A.	CNAT	Common Stock	J - Other	D		11.0000	16,742	184		1,321,795
2013-08-01	2013-07-30	4	COOPERATIVE GILDE HEALTHCARE II U.A.	CNAT	Common Stock	S - Sale	D		11.0000	-352	-4		1,305,053
2013-08-01	2013-07-30	4	COOPERATIVE GILDE HEALTHCARE II U.A.	CNAT	Common Stock	X - Other	D			46,675			1,305,405
2013-08-01	2013-07-30	4	COOPERATIVE GILDE HEALTHCARE II U.A.	CNAT	Common Stock	C - Conversion	D			1,258,730			1,258,730
2013-08-01	2013-07-30	4	Aberdare GP III, L.L.C. By Aberdare Partners III, L.P.	CNAT	Warrant to Purchase Common Stock	C - Conversion	I	7.43		120		120
2013-08-01	2013-07-30	4	Aberdare GP III, L.L.C. By Aberdare Partners III, L.P.	CNAT	Warrant to Purchase Series B Preferred Stock	C - Conversion	I	0.90		-997		0
2013-08-01	2013-07-30	4	Aberdare GP III, L.L.C. By Aberdare Partners III, L.P.	CNAT	Warrant to Purchase Common Stock	X - Other	I	0.08		-1,727		0
2013-08-01	2013-07-30	4	Aberdare GP III, L.L.C. By Aberdare Partners III, L.P.	CNAT	Warrant to Purchase Common Stock	C - Conversion	I	0.08		1,727		1,727
2013-08-01	2013-07-30	4	Aberdare GP III, L.L.C. By Aberdare Partners III, L.P.	CNAT	Warrant to Purchase Series A Preferred Stock	C - Conversion	I	0.01		-5,701		0
2013-08-01	2013-07-30	4	Aberdare GP III, L.L.C. By Aberdare Partners III, L.P.	CNAT	Warrant to Purchase Series A Preferred Stock	C - Conversion	I	0.01		-8,552		0
2013-08-01	2013-07-30	4	Aberdare GP III, L.L.C. By Aberdare Partners III, L.P.	CNAT	Series B Preferred Stock	C - Conversion	I			-137,626		0
2013-08-01	2013-07-30	4	Aberdare GP III, L.L.C. By Aberdare Partners III, L.P.	CNAT	Series A Preferred Stock	C - Conversion	I			-246,775		0
2013-08-01	2013-07-30	4	Aberdare GP III, L.L.C. By Aberdare Ventures III, L.P.	CNAT	Warrant to Purchase Common Stock	C - Conversion	I	7.43		5,131		5,131
2013-08-01	2013-07-30	4	Aberdare GP III, L.L.C. By Aberdare Ventures III, L.P.	CNAT	Warrant to Purchase Common Stock	C - Conversion	I	0.90		-42,336		0
2013-08-01	2013-07-30	4	Aberdare GP III, L.L.C. By Aberdare Ventures III, L.P.	CNAT	Warrant to Purchase Common Stock	X - Other	I	0.08		-73,395		0
2013-08-01	2013-07-30	4	Aberdare GP III, L.L.C. By Aberdare Ventures III, L.P.	CNAT	Warrant to Purchase Common Stock	C - Conversion	I	0.08		73,395		73,395
2013-08-01	2013-07-30	4	Aberdare GP III, L.L.C. By Aberdare Ventures III, L.P.	CNAT	Warrant to Purchase Series A Preferred Stock	C - Conversion	I	0.01		-242,205		0
2013-08-01	2013-07-30	4	Aberdare GP III, L.L.C. By Aberdare Ventures III, L.P.	CNAT	Warrant to Purchase Series A Preferred Stock	C - Conversion	I	0.01		-363,308		0
2013-08-01	2013-07-30	4	Aberdare GP III, L.L.C. By Aberdare Ventures III, L.P.	CNAT	Series B Preferred Stock	C - Conversion	I			-5,846,236		0
2013-08-01	2013-07-30	4	Aberdare GP III, L.L.C. By Aberdare Ventures III, L.P.	CNAT	Series A Preferred Stock	C - Conversion	I			-10,483,166		0
2013-08-01	2013-07-30	4	Aberdare GP III, L.L.C. By Aberdare Partners III, L.P.	CNAT	Common Stock	P - Purchase	I		11.0000	2,470	27		52,419
2013-08-01	2013-07-30	4	Aberdare GP III, L.L.C. By Aberdare Partners III, L.P.	CNAT	Common Stock	J - Other	I		11.0000	251	3		49,949
2013-08-01	2013-07-30	4	Aberdare GP III, L.L.C. By Aberdare Partners III, L.P.	CNAT	Common Stock	S - Sale	I		11.0000	-14	-0		49,698
2013-08-01	2013-07-30	4	Aberdare GP III, L.L.C. By Aberdare Partners III, L.P.	CNAT	Common Stock	X - Other	I		0.0825	1,727	0		49,712
2013-08-01	2013-07-30	4	Aberdare GP III, L.L.C. By Aberdare Partners III, L.P.	CNAT	Common Stock	C - Conversion	I			46,594			47,985
2013-08-01	2013-07-30	4	Aberdare GP III, L.L.C. By Aberdare Ventures III, L.P.	CNAT	Common Stock	P - Purchase	I		11.0000	104,952	1,154		2,226,944
2013-08-01	2013-07-30	4	Aberdare GP III, L.L.C. By Aberdare Ventures III, L.P.	CNAT	Common Stock	J - Other	I		11.0000	10,614	117		2,121,992
2013-08-01	2013-07-30	4	Aberdare GP III, L.L.C. By Aberdare Ventures III, L.P.	CNAT	Common Stock	S - Sale	I		11.0000	-552	-6		2,111,378
2013-08-01	2013-07-30	4	Aberdare GP III, L.L.C. By Aberdare Ventures III, L.P.	CNAT	Common Stock	X - Other	I		0.0825	73,395	6		2,111,930
2013-08-01	2013-07-30	4	Aberdare GP III, L.L.C. By Aberdare Ventures III, L.P.	CNAT	Common Stock	C - Conversion	I			1,979,321			2,038,535
2013-08-01	2013-07-30	4	KLINGENSTEIN PAUL H	CNAT	Stock Option (right to buy)	A - Award	D	11.00		30,000		30,000
2013-08-01	2013-07-30	4	KLINGENSTEIN PAUL H By Aberdare Partners III, L.P.	CNAT	Warrant to Purchase Common Stock	C - Conversion	I	7.43		120		120
2013-08-01	2013-07-30	4	KLINGENSTEIN PAUL H By Aberdare Partners III, L.P.	CNAT	Warrant to Purchase Series B Preferred Stock	C - Conversion	I	0.90		-997		0
2013-08-01	2013-07-30	4	KLINGENSTEIN PAUL H By Aberdare Partners III, L.P.	CNAT	Warrant to Purchase Common Stock	X - Other	I	0.08		-1,727		0
2013-08-01	2013-07-30	4	KLINGENSTEIN PAUL H By Aberdare Partners III, L.P.	CNAT	Warrant to Purchase Common Stock	C - Conversion	I	0.08		1,727		1,727
2013-08-01	2013-07-30	4	KLINGENSTEIN PAUL H By Aberdare Partners III, L.P.	CNAT	Warrant to Purchase Series A Preferred Stock	C - Conversion	I	0.01		-5,701		0
2013-08-01	2013-07-30	4	KLINGENSTEIN PAUL H By Aberdare Partners III, L.P.	CNAT	Warrant to Purchase Series A Preferred Stock	C - Conversion	I	0.01		-8,552		0
2013-08-01	2013-07-30	4	KLINGENSTEIN PAUL H By Aberdare Partners III, L.P.	CNAT	Series B Preferred Stock	C - Conversion	I			-137,626		0
2013-08-01	2013-07-30	4	KLINGENSTEIN PAUL H By Aberdare Partners III, L.P.	CNAT	Series A Preferred Stock	C - Conversion	I			-246,775		0
2013-08-01	2013-07-30	4	KLINGENSTEIN PAUL H By Aberdare Ventures III, L.P.	CNAT	Warrant to Purchase Common Stock	C - Conversion	I	7.43		5,131		5,131
2013-08-01	2013-07-30	4	KLINGENSTEIN PAUL H By Aberdare Ventures III, L.P.	CNAT	Warrant to Purchase Common Stock	C - Conversion	I	0.90		-42,336		0
2013-08-01	2013-07-30	4	KLINGENSTEIN PAUL H By Aberdare Ventures III, L.P.	CNAT	Warrant to Purchase Common Stock	X - Other	I	0.08		-73,395		0
2013-08-01	2013-07-30	4	KLINGENSTEIN PAUL H By Aberdare Ventures III, L.P.	CNAT	Warrant to Purchase Common Stock	C - Conversion	I	0.08		73,395		73,395
2013-08-01	2013-07-30	4	KLINGENSTEIN PAUL H By Aberdare Ventures III, L.P.	CNAT	Warrant to Purchase Series A Preferred Stock	C - Conversion	I	0.01		-242,205		0
2013-08-01	2013-07-30	4	KLINGENSTEIN PAUL H By Aberdare Ventures III, L.P.	CNAT	Warrant to Purchase Series A Preferred Stock	C - Conversion	I	0.01		-363,308		0
2013-08-01	2013-07-30	4	KLINGENSTEIN PAUL H By Aberdare Ventures III, L.P.	CNAT	Series B Preferred Stock	C - Conversion	I			-5,846,236		0
2013-08-01	2013-07-30	4	KLINGENSTEIN PAUL H By Aberdare Ventures III, L.P.	CNAT	Series A Preferred Stock	C - Conversion	I			-10,483,166		0
2013-08-01	2013-07-30	4	KLINGENSTEIN PAUL H By Aberdare Partners III, L.P.	CNAT	Common Stock	P - Purchase	I		11.0000	2,470	27		52,419
2013-08-01	2013-07-30	4	KLINGENSTEIN PAUL H By Aberdare Partners III, L.P.	CNAT	Common Stock	J - Other	I		11.0000	251	3		49,949
2013-08-01	2013-07-30	4	KLINGENSTEIN PAUL H By Aberdare Partners III, L.P.	CNAT	Common Stock	S - Sale	I		11.0000	-14	-0		49,698
2013-08-01	2013-07-30	4	KLINGENSTEIN PAUL H By Aberdare Partners III, L.P.	CNAT	Common Stock	X - Other	I		0.0825	1,727	0		49,712
2013-08-01	2013-07-30	4	KLINGENSTEIN PAUL H By Aberdare Partners III, L.P.	CNAT	Common Stock	C - Conversion	I			46,594			47,985
2013-08-01	2013-07-30	4	KLINGENSTEIN PAUL H By Aberdare Ventures III, L.P.	CNAT	Common Stock	P - Purchase	I		11.0000	104,952	1,154		2,226,944
2013-08-01	2013-07-30	4	KLINGENSTEIN PAUL H By Aberdare Ventures III, L.P.	CNAT	Common Stock	J - Other	I		11.0000	10,614	117		2,121,992
2013-08-01	2013-07-30	4	KLINGENSTEIN PAUL H By Aberdare Ventures III, L.P.	CNAT	Common Stock	S - Sale	I		11.0000	-552	-6		2,111,378
2013-08-01	2013-07-30	4	KLINGENSTEIN PAUL H By Aberdare Ventures III, L.P.	CNAT	Common Stock	X - Other	I		0.0825	73,395	6		2,111,930
2013-08-01	2013-07-30	4	KLINGENSTEIN PAUL H By Aberdare Ventures III, L.P.	CNAT	Common Stock	C - Conversion	I			1,979,321			2,038,535
2013-07-24		3	HALE DAVID F	CNAT	Common Stock		I						121,211
2013-07-24		3	Mento Steven J	CNAT	Common Stock		I						275,151
2013-07-24		3	Cashion Charles	CNAT	Common Stock		I						106,666
2013-07-24		3	Spada Alfred P.	CNAT	Common Stock		I						190,909
2013-07-24		3	BURGESS GARY C.	CNAT	Common Stock		D						121,212
2013-07-24		3	Aberdare Partners III LP By Aberdare Partners III, L.P.	CNAT	Common Stock		I						1,391
2013-07-24		3	Aberdare Partners III LP By Aberdare Ventures III, L.P.	CNAT	Common Stock		I						59,214
2013-07-24		3	KLINGENSTEIN PAUL H By Aberdare Partners III, L.P.	CNAT	Common Stock		I						1,391
2013-07-24		3	KLINGENSTEIN PAUL H By Aberdare Ventures III, L.P.	CNAT	Common Stock		I						59,214

Compra de mercado aberto ou privada de ativo não-derivativo ou derivativo

Venda de mercado aberto ou privada de ativo não-derivativo ou derivativo

Concessão, premiação, ou outra aquisição de ativos da empresa (como uma opção)

Conversão de derivativo

Venda ou transferência de ativos de volta para a empresa

Pagamento do preço de exercício ou responsabilidade fiscal utilizando parte dos ativos recebidos da empresa

Doação de ativos pelo ou para o insider

Swaps de capital e transações de hedge similares

Exercício ou conversão de ativo derivativo recebido da empresa (como uma opção)

Uma transação voluntariamente reportada no Formulário 4

Outro (acompanhado de uma nota explicativa descrevendo a transação)

HSTO / Histogen Inc. - Insider Trading and Ownership Report - SEC Form 3, 4, 5