| Ações em Circulação | 15,801,901 shares |
| Ações de Insider | 8,617,263 shares |
| Propriedade de Insider | 54.53 % |
| Total de Insiders | 44 |
Pontuação de Sentimento de Insider
A Pontuação de Sentimento de Insider encontra as empresas que estão sendo compradas por insiders corporativos.
É o resultado de um modelo quantitativo sofisticado e multifatorial que identifica empresas com os mais altos níveis de acumulação por insiders. O modelo de pontuação usa uma combinação do número líquido de insiders comprando nos últimos 90 dias, o total de ações compradas como um percentual do float, e o total de ações possuídas por insiders. A escala varia de 0 a 100, com números mais altos indicando um maior nível de acumulação em relação aos seus pares, e 50 sendo a média.
Frequência de Atualização: Diariamente
Pontuação de Sentimento dos Oficiais
A Pontuação de Sentimento de Officer encontra empresas que estão sendo compradas por Oficiais Corporativos.
Por definição, Oficiais Corporativos são Insiders Corporativos, mas, ao contrário de alguns outros Insiders (Acionistas de 10% e Membros do Conselho), os Oficiais trabalham para a empresa diariamente, e eles usam seu próprio dinheiro ao negociar. (Acionistas de 10% e Membros do Conselho muitas vezes são gestores de fundos que gerenciam o dinheiro de outras pessoas.) Como tal, as negociações de insiders feitas por Oficiais são muito mais significativas e devem ser tratadas apropriadamente.
Como a Pontuação de Sentimento dos Insiders, a Pontuação de Sentimento de Officer é o resultado de um modelo quantitativo sofisticado e multifatorial que identifica empresas com os mais altos níveis de acumulação por parte dos oficiais.
Frequência de Atualização: Diariamente
Principais Métricas de Insider
Este cartão mostra como a empresa se classifica em várias métricas internas. O percentil mostra como esta empresa se compara a outras empresas nos mercados dos EUA. Classificações mais altas são indicativas de situações melhores.
Por exemplo, geralmente aceita-se que a compra interna é um indicador positivo, portanto, empresas com mais compras internas teriam classificações mais altas do que empresas com menos compras internas (ou até mesmo venda interna).
Percentual do Float Comprado por Insiders (Classificação)
10495 out of 10786
Percentual do Float Comprado por Insiders é o número total de ações compradas por insiders menos o número total de ações vendidas por insiders nos últimos 90 dias, dividido pelo total flutuante e multiplicado por 100.
Gráfico de Negociação de Insider
Neurogene Inc. negociações de insiders são mostradas no seguinte gráfico. Insiders são oficiais, diretores ou investidores significativos em uma empresa. Em geral, é geralmente ilegal para insiders realizarem negociações em suas empresas com base em informações materiais, não públicas. Isso não significa que seja ilegal para eles fazerem quaisquer negociações em suas próprias empresas. No entanto, eles devem relatar todas as negociações à SEC através de um Formulário 4.
Roster de Insider e Métricas de Lucratividade
Esta tabela mostra a lista de insiders conhecidos, e é gerada automaticamente a partir de arquivamentos divulgados à SEC. Além dos nomes, título mais recente, e designação de diretor, oficial ou proprietário de 10%, fornecemos as últimas participações divulgadas. Adicionalmente, quando possível fornecemos o desempenho comercial histórico do insider. O desempenho comercial histórico é uma média ponderada do desempenho de transações reais de compra no mercado aberto feitas pelo insider. Para mais informações sobre como isso é calculado, assista este webinar no YouTube.
See our leaderboard of most profitable insider traders.
| Insider | Lucro Médio (%) | Ações Possuídas |
Ajuste de Divisão |
|---|---|---|---|
| Kamran Alam CFO, Vice President Finance - [O] | 0 | 0 | |
|
Baker Bros. Advisors Lp
Director, 10% Owner -
[D]
|
1,658,190 | 1,658,190 | |
|
Julian Baker
10% Owner -
|
3,501,691 | 1,658,190 | |
| Martin Babler | 25,000 | ||
|
Baker Bros. Advisors (GP) LLC
10% Owner -
|
25,000 | 1,658,190 | |
| Meta Cantey Boyd | 0 | ||
| Gary Bridger Director - [D] | 0 | 0 | |
| Stuart Cobb Chief Scientific Officer - [O] | 30,497 | 30,497 | |
| Donna Cochener | 400,000 | ||
| Christine Mikail Cvijic President and CFO, Director - [D] [O] | 93,640 | 93,640 | |
| Jonathan G Drachman President and CEO, Director - [D] [O] | 100,000 | 20,000 | |
|
Jeremy Green
10% Owner -
|
4,041,211 | 808,242 | |
| Robert Ho Chief Financial Officer - [O] | 21,503 | 4,301 | |
|
& Johnson Johnson
10% Owner -
|
100,000 | 100,000 |
| Insider | Lucro Médio (%) | Ações Possuídas |
Ajuste de Divisão |
|---|---|---|---|
| Abigail Jenkins Chief Commercial Officer - [O] | 0 | 0 | |
|
Johnson & Johnson Innovation - JJDC, Inc.
10% Owner -
|
100,000 | 100,000 | |
| Elaine V Jones Director - [D] | 0 | 0 | |
| Julie Jordan Chief Medical Officer - [O] | 12,472 | 12,472 | |
| Daniel J Levitt Director - [D] | 0 | 0 | |
| Erin Lavelle | 25,000 | ||
| Lavelle Erin M. | 0 | ||
| Richard S Levy | 0 | ||
| Lloyd MacKenzie Chief Operating Officer - [O] | 0 | 0 | |
| David Main President and CEO, Director - [D] [O] | 71,530 | 71,530 | |
| Shelley McCloskey VP, HR and Administration - [O] | 0 | 0 | |
| Rachel McMinn Chief Executive Officer, Director - [D] [O] | 1,344,307 | 1,344,307 | |
| David Chilton Mitchell VP Global Regulatory & Quality - [O] | 3,575 | 3,575 | |
| Kelvin Neu Director - [D] | 72 | 72 | |
| Nolan Sean P. | 25,000 |
| Insider | Lucro Médio (%) | Ações Possuídas |
Ajuste de Divisão |
|---|---|---|---|
| Noonberg Sarah B. | 25,000 | ||
| Rohan Palekar | 25,000 | ||
|
Pfizer Inc
10% Owner -
|
975,403 | 975,403 | |
| Priti Patel - | 37,313 | 7,463 | |
| Robert Pelzer | 15,000 | ||
|
Redmile Group, LLC
10% Owner -
|
4,041,211 | 808,242 | |
| Stephen B Shrewsbury CMO; Senior VP Clinical Dev. - [O] | 400 | 400 | |
| Todd E Simpson Director - [D] | 0 | 0 | |
|
Samsara BioCapital GP, LLC
10% Owner -
|
1,668,357 | 1,668,357 | |
| Sean Michael Smith Interim CFO, Prin Acct Off - [O] | 21,637 | 4,327 | |
| Barbara Troupin Chief Medical Officer - [O] | 0 | 0 | |
| Holly Vance | 100,000 | ||
|
Ventures West 8 Limited Partnership
10% Owner -
|
1,543,989 | 1,543,989 | |
| Carl Walkey Senior Vice President - [O] | 1,352,489 | 270,498 | |
| Lewis T Williams | 25,000 |
Report errors via our new Insider Auditing Tool
Acompanhar Históricos de Compras de Insiders - Análise de Lucro a Curto Prazo
Nesta seção, analisamos a lucratividade de cada compra de insider não planejada, feita no mercado aberto em NGNE / Neurogene Inc.. Esta análise ajuda a entender se o insider gera consistentemente retornos anormais, e vale a pena ser seguido. Esta análise é para um ano após cada negociação, e os resultados são teóricos .
A tabela a seguir mostra as compras mais recentes no mercado aberto que não fizeram parte de um plano de negociação automática.
Preço Ajustado é o preço ajustado pelo desdobramento. Ações Ajustadas são as ações ajustadas pelo desdobramento.
Acompanhar Históricos de Vendas de Insiders - Análise de Perda a Curto Prazo
Nesta seção, analisamos a evitação de perda de curto prazo de cada venda de insider não planejada, feita no mercado aberto em NGNE / Neurogene Inc.. Um padrão consistente de evitação de perdas pode sugerir que transações de venda futuras possam prever quedas no preço. Esta análise é para um ano após cada negociação, e os resultados são teóricos .
A tabela a seguir mostra as vendas mais recentes no mercado aberto que não fizeram parte de um plano de negociação automática.
Preço Ajustado é o preço ajustado pelo desdobramento. Ações Ajustadas são as ações ajustadas pelo desdobramento.
Histórico de Transações
Clique no ícone de link para ver o histórico completo de transações. As transações relatadas como parte de um plano de negociação automática 10b5-1 terão um X na coluna marcada como 10b-5.
| Arquivo Data |
Data da Operação |
Formulário | Insider | Ticker | Título de Segurança | Código | Direto | Preço de Exercício Preço Unitário |
Preço por Unidade |
Unidades Alteradas |
Valor Alterado (1K) |
Opções Restantes |
Ações Restantes |
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026-05-08 | 2026-05-06 | 4 | Cvijic Christine Mikail | NGNE | Common Stock | D | 32.4358 | -4,800 | -156 | 93,640 | ||||
| 2026-05-08 | 2026-05-06 | 4 | Cvijic Christine Mikail | NGNE | Common Stock | D | 30.0732 | -4,800 | -144 | 98,440 | ||||
| 2026-03-30 | 2026-03-26 | 4 | Cvijic Christine Mikail | NGNE | Common Stock | D | 21.6247 | -2,558 | -55 | 103,240 | ||||
| 2026-03-30 | 2026-03-26 | 4 | Jordan Julie | NGNE | Common Stock | D | 21.8932 | -828 | -18 | 12,472 | ||||
| 2026-03-30 | 2026-03-26 | 4 | McMinn Rachel | NGNE | Common Stock | D | 22.0749 | -3,352 | -74 | 1,344,307 | ||||
| 2026-03-17 | 2026-03-13 | 4 | Cvijic Christine Mikail | NGNE | Common Stock | D | 22.0195 | -263 | -6 | 105,798 | ||||
| 2026-03-17 | 2026-03-13 | 4 | Cvijic Christine Mikail | NGNE | Common Stock | D | 21.2451 | -1,395 | -30 | 106,061 | ||||
| 2026-03-17 | 2026-03-13 | 4 | Cvijic Christine Mikail | NGNE | Common Stock | D | 20.4224 | -2,387 | -49 | 107,456 | ||||
| 2026-03-17 | 2026-03-13 | 4 | Cobb Stuart | NGNE | Common Stock | D | 22.0800 | -148 | -3 | 30,497 | ||||
| 2026-03-17 | 2026-03-13 | 4 | Cobb Stuart | NGNE | Common Stock | D | 21.3400 | -2,658 | -57 | 30,645 | ||||
| 2026-03-17 | 2026-03-13 | 4 | Cobb Stuart | NGNE | Common Stock | D | 20.4100 | -3,991 | -81 | 33,303 | ||||
| 2026-03-03 | 2026-02-27 | 4 | Cvijic Christine Mikail | NGNE | Common Stock | D | 25.1096 | -4,800 | -121 | 109,843 | ||||
| 2026-02-24 | 2026-02-20 | 4 | Cobb Stuart | NGNE | Common Stock | D | 16,500 | 37,294 | ||||||
| 2026-02-24 | 2026-02-20 | 4 | Cvijic Christine Mikail | NGNE | Common Stock | D | 22,000 | 114,643 | ||||||
| 2026-02-24 | 2026-02-20 | 4 | Jordan Julie | NGNE | Common Stock | D | 4,900 | 13,300 | ||||||
| 2026-02-24 | 2026-02-20 | 4 | McMinn Rachel | NGNE | Common Stock | D | 25,900 | 1,347,659 | ||||||
| 2025-05-15 | 2025-05-14 | 4 | Cobb Stuart | NGNE | Common Stock | D | 15.1542 | -6,797 | -103 | 20,794 | ||||
| 2025-03-28 | 2025-03-26 | 4 | Cobb Stuart | NGNE | Common Stock | D | 7,200 | 27,591 | ||||||
| 2025-03-28 | 2025-03-26 | 4 | Cvijic Christine Mikail | NGNE | Common Stock | D | 20,300 | 92,643 | ||||||
| 2025-03-28 | 2025-03-26 | 4 | Jordan Julie | NGNE | Common Stock | D | 8,400 | 8,400 | ||||||
| 2025-03-28 | 2025-03-26 | 4 | McMinn Rachel | NGNE | Common Stock | D | 23,900 | 1,274,259 | ||||||
| 2025-03-17 | 2025-03-13 | 4 | Cvijic Christine Mikail | NGNE | Common Stock | D | 16.9400 | -4,501 | -76 | 72,343 | ||||
| 2024-11-27 | 2024-11-26 | 4 | Samsara BioCapital GP, LLC By Samsara BioCapital, L.P. | NGNE | Common Stock | I | 27.5000 | 2,000 | 55 | 1,717,127 | ||||
| 2024-11-27 | 2024-11-26 | 4 | Samsara BioCapital GP, LLC By Samsara BioCapital, L.P. | NGNE | Common Stock | I | 26.7300 | 15,219 | 407 | 1,715,127 | ||||
| 2024-11-27 | 2024-11-26 | 4 | Samsara BioCapital GP, LLC By Samsara BioCapital, L.P. | NGNE | Common Stock | I | 26.0100 | 10,803 | 281 | 1,699,908 | ||||
| 2024-11-27 | 2024-11-26 | 4 | Samsara BioCapital GP, LLC By Samsara BioCapital, L.P. | NGNE | Common Stock | I | 24.9100 | 20,748 | 517 | 1,689,105 | ||||
| 2024-11-27 | 3 | Samsara BioCapital GP, LLC By Samsara BioCapital, L.P. | NGNE | Common Stock | I | 1,668,357 | ||||||||
| 2024-11-25 | 2024-11-22 | 4 | McMinn Rachel | NGNE | Common Stock | D | 20.4000 | 47,500 | 969 | 1,297,859 | ||||
| 2024-11-25 | 2024-11-22 | 4 | Cvijic Christine Mikail | NGNE | Common Stock | D | 20.4750 | 24,000 | 491 | 76,844 | ||||
| 2024-03-14 | 2024-03-13 | 4 | Cvijic Christine Mikail | NGNE | Common Stock | D | 31,903 | 52,844 | ||||||
| 2024-03-14 | 2024-03-13 | 4 | Cobb Stuart | NGNE | Common Stock | D | 20,391 | 20,391 | ||||||
| 2023-12-26 | 3 | Cvijic Christine Mikail | NGNE | Common Stock | D | 20,941 | ||||||||
| 2023-12-26 | 3 | McMinn Rachel | NGNE | Common Stock | D | 1,250,359 | ||||||||
| 2023-10-10 | 2023-10-05 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Common Stock | I | 535,601 | 1,658,190 | ||||||
| 2023-10-10 | 2023-10-05 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Common Stock | I | 57,049 | 155,874 | ||||||
| 2023-08-17 | 2023-08-17 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Common Stock | I | 0.6928 | 61,134 | 42 | 5,612,949 | ||||
| 2023-08-17 | 2023-08-17 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Common Stock | I | 0.6928 | 5,041 | 3 | 494,133 | ||||
| 2023-08-17 | 2023-08-17 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Common Stock | I | 0.6924 | 93,091 | 64 | 5,551,815 | ||||
| 2023-08-17 | 2023-08-17 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Common Stock | I | 0.6924 | 7,676 | 5 | 489,092 | ||||
| 2023-08-17 | 2023-08-16 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Common Stock | I | 0.6828 | 4,434 | 3 | 5,458,724 | ||||
| 2023-08-17 | 2023-08-16 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Common Stock | I | 0.6828 | 366 | 0 | 481,416 | ||||
| 2023-08-17 | 2023-08-16 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Common Stock | I | 0.6805 | 207,676 | 141 | 5,454,290 | ||||
| 2023-08-17 | 2023-08-16 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Common Stock | I | 0.6805 | 17,124 | 12 | 481,050 | ||||
| 2023-08-17 | 2023-08-15 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Common Stock | I | 0.6650 | 4,342 | 3 | 5,246,614 | ||||
| 2023-08-17 | 2023-08-15 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Common Stock | I | 0.6650 | 358 | 0 | 463,926 | ||||
| 2023-08-17 | 2023-08-15 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Common Stock | I | 0.6308 | 1,740,581 | 1,098 | 5,242,272 | ||||
| 2023-08-17 | 2023-08-15 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Common Stock | I | 0.6308 | 143,519 | 91 | 463,568 | ||||
| 2023-08-14 | 2023-08-11 | 4 | Smith Sean Michael | NLTX | Common Stock | D | 0.6184 | -1,323 | -1 | 21,637 | ||||
| 2023-08-14 | 2023-08-10 | 4 | Smith Sean Michael | NLTX | Common Stock | D | 5,000 | 22,960 | ||||||
| 2023-04-04 | 2023-04-03 | 4 | Patel Priti | NLTX | Common Stock | D | 0.6919 | -3,769 | -3 | 37,313 | ||||
| 2023-04-04 | 2023-03-31 | 4 | Patel Priti | NLTX | Common Stock | D | 10,000 | 41,082 | ||||||
| 2023-02-03 | 2023-02-02 | 4 | Patel Priti | NLTX | Common Stock | D | 0.5972 | -14,380 | -9 | 31,082 | ||||
| 2023-02-03 | 2023-02-01 | 4 | Patel Priti | NLTX | Common Stock | D | 35,000 | 45,462 | ||||||
| 2023-02-03 | 2023-02-02 | 4 | Smith Sean Michael | NLTX | Common Stock | D | 0.5972 | -3,316 | -2 | 15,960 | ||||
| 2023-02-03 | 2023-02-01 | 4 | Smith Sean Michael | NLTX | Common Stock | D | 12,500 | 19,276 | ||||||
| 2022-08-12 | 2022-08-10 | 4 | Smith Sean Michael | NLTX | Common Stock | D | 0.9914 | -1,655 | -2 | 6,776 | ||||
| 2022-08-12 | 2022-08-10 | 4 | Smith Sean Michael | NLTX | Common Stock | D | 5,000 | 8,431 | ||||||
| 2022-05-16 | 2022-05-12 | 4 | SIMPSON TODD E | NLTX | Stock Option (Right to Buy) | D | 1.07 | 25,000 | 25,000 | |||||
| 2022-05-16 | 2022-05-12 | 4 | PALEKAR ROHAN | NLTX | Stock Option (Right to Buy) | D | 1.07 | 25,000 | 25,000 | |||||
| 2022-05-16 | 2022-05-12 | 4 | Lavelle Erin | NLTX | Stock Option (Right to Buy) | D | 1.07 | 25,000 | 25,000 | |||||
| 2022-05-16 | 2022-05-12 | 4 | Noonberg Sarah B. | NLTX | Stock Option (Right to Buy) | D | 1.07 | 25,000 | 25,000 | |||||
| 2022-05-16 | 2022-05-12 | 4 | Babler Martin | NLTX | Stock Option (Right to Buy) | D | 1.07 | 25,000 | 25,000 | |||||
| 2022-05-16 | 2022-05-12 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Non-Qualified Stock Option (right to buy) | I | 1.07 | 25,000 | 25,000 | |||||
| 2022-05-03 | 2022-05-02 | 4 | Patel Priti | NLTX | Common Stock | D | 1.2186 | -5,538 | -7 | 6,462 | ||||
| 2022-05-03 | 2022-04-30 | 4 | Patel Priti | NLTX | Restricted Stock Units | D | 0.00 | 10,000 | 10,000 | |||||
| 2022-05-03 | 2022-04-30 | 4 | Patel Priti | NLTX | Common Stock | D | 10,000 | 12,000 | ||||||
| 2022-03-15 | 2022-03-14 | 4 | Cochener Donna | NLTX | Stock Option (Right to Buy) | D | 1.81 | 400,000 | 400,000 | |||||
| 2022-03-04 | 2022-03-02 | 4 | PALEKAR ROHAN | NLTX | Stock Option (Right to Buy) | D | 2.72 | 50,000 | 50,000 | |||||
| 2022-03-03 | 3 | Smith Sean Michael | NLTX | Common Stock | D | 3,431 | ||||||||
| 2022-03-03 | 2022-03-02 | 4 | Smith Sean Michael | NLTX | Stock Option (Right to Buy) | D | 2.72 | 80,000 | 80,000 | |||||
| 2022-02-14 | 2021-10-26 | 5 | DRACHMAN JONATHAN G | NLTX | Common Stock | I | 75,000 | 100,000 | ||||||
| 2022-02-14 | 2021-10-26 | 5 | DRACHMAN JONATHAN G | NLTX | Common Stock | I | 75,000 | 100,000 | ||||||
| 2022-02-14 | 2021-10-26 | 5 | DRACHMAN JONATHAN G | NLTX | Common Stock | D | -75,000 | 2,198,686 | ||||||
| 2022-02-14 | 2021-10-26 | 5 | DRACHMAN JONATHAN G | NLTX | Common Stock | D | -75,000 | 2,198,686 | ||||||
| 2022-02-02 | 2022-02-01 | 4 | Walkey Carl | NLTX | Restricted Stock Units | D | 0.00 | 55,000 | 55,000 | |||||
| 2022-02-02 | 2022-02-01 | 4 | Patel Priti | NLTX | Restricted Stock Units | D | 0.00 | 70,000 | 70,000 | |||||
| 2022-02-02 | 2022-02-01 | 4 | Ho Robert | NLTX | Restricted Stock Units | D | 0.00 | 70,000 | 70,000 | |||||
| 2021-08-26 | 2021-08-25 | 4 | DRACHMAN JONATHAN G | NLTX | Common Stock | I | 6.4490 | 25,000 | 161 | 25,000 | ||||
| 2021-08-26 | 2021-08-25 | 4 | DRACHMAN JONATHAN G | NLTX | Common Stock | I | 6.4490 | 25,000 | 161 | 25,000 | ||||
| 2021-08-26 | 2021-08-24 | 4 | DRACHMAN JONATHAN G | NLTX | Common Stock | D | 6.1110 | 100,000 | 611 | 2,348,686 | ||||
| 2021-08-05 | 2021-08-03 | 4 | Walkey Carl | NLTX | Stock Option (Right to Buy) | D | 6.80 | 100,000 | 100,000 | |||||
| 2021-08-05 | 2021-08-03 | 4 | Vance Holly | NLTX | Stock Option (Right to Buy) | D | 6.80 | 100,000 | 100,000 | |||||
| 2021-08-05 | 2021-08-03 | 4 | Patel Priti | NLTX | Stock Option (Right to Buy) | D | 6.80 | 50,000 | 50,000 | |||||
| 2021-08-05 | 2021-08-03 | 4 | Ho Robert | NLTX | Stock Option (Right to Buy) | D | 6.80 | 190,000 | 190,000 | |||||
| 2021-08-05 | 2021-08-03 | 4 | DRACHMAN JONATHAN G | NLTX | Stock Option (Right to Buy) | D | 6.80 | 400,000 | 400,000 | |||||
| 2021-06-17 | 2021-06-16 | 4 | Walkey Carl | NLTX | Common Stock | D | 10.1900 | -600 | -6 | 1,352,489 | ||||
| 2021-06-11 | 2021-06-09 | 4 | Walkey Carl | NLTX | Common Stock | D | 10.8246 | -650 | -7 | 1,353,089 | ||||
| 2021-06-09 | 2021-06-08 | 4 | Walkey Carl | NLTX | Common Stock | D | 11.0000 | -600 | -7 | 1,353,739 | ||||
| 2021-06-07 | 2021-06-04 | 4 | Walkey Carl | NLTX | Common Stock | D | 10.0000 | -600 | -6 | 1,354,339 | ||||
| 2021-06-07 | 2021-06-04 | 4 | DRACHMAN JONATHAN G | NLTX | Common Stock | D | 9.6082 | 10,000 | 96 | 2,248,686 | ||||
| 2021-06-07 | 2021-06-03 | 4 | DRACHMAN JONATHAN G | NLTX | Common Stock | D | 9.4818 | 40,000 | 379 | 2,238,686 | ||||
| 2021-05-26 | 2021-05-26 | 4 | Walkey Carl | NLTX | Common Stock | D | 10.0000 | -600 | -6 | 1,354,939 | ||||
| 2021-05-21 | 2021-05-19 | 4 | Walkey Carl | NLTX | Common Stock | D | 10.6300 | -600 | -6 | 1,355,539 | ||||
| 2021-05-13 | 2021-05-11 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Non-Qualified Stock Option (right to buy) | I | 11.40 | 25,000 | 25,000 | |||||
| 2021-05-13 | 2021-05-11 | 4 | Babler Martin | NLTX | Stock Option (Right to Buy) | D | 11.40 | 25,000 | 25,000 | |||||
| 2021-05-13 | 2021-05-11 | 4 | Lavelle Erin M. | NLTX | Stock Option (Right to Buy) | D | 11.40 | 25,000 | 25,000 | |||||
| 2021-05-13 | 2021-05-11 | 4 | Noonberg Sarah B. | NLTX | Stock Option (Right to Buy) | D | 11.40 | 25,000 | 25,000 | |||||
| 2021-05-13 | 2021-05-11 | 4 | Williams Lewis T | NLTX | Stock Option (Right to Buy) | D | 11.40 | 25,000 | 25,000 | |||||
| 2021-05-13 | 2021-05-11 | 4 | SIMPSON TODD E | NLTX | Stock Option (Right to Buy) | D | 11.40 | 25,000 | 25,000 | |||||
| 2021-05-12 | 2021-05-12 | 4 | Walkey Carl | NLTX | Common Stock | D | 11.0900 | -1,200 | -13 | 1,354,762 | ||||
| 2021-05-06 | 2021-05-05 | 4 | Walkey Carl | NLTX | Common Stock | D | 11.3000 | -1,200 | -14 | 1,355,962 | ||||
| 2021-05-04 | 2021-04-30 | 4 | Patel Priti | NLTX | Stock Option (Right to Buy) | D | 12.49 | 475,000 | 475,000 | |||||
| 2021-05-04 | 2021-04-30 | 4 | Patel Priti | NLTX | Restricted Stock Units | D | 0.00 | 20,000 | 20,000 | |||||
| 2021-04-30 | 2021-04-28 | 4 | Walkey Carl | NLTX | Common Stock | D | 12.5800 | -2,400 | -30 | 1,357,162 | ||||
| 2021-04-27 | 2021-04-26 | 4 | Walkey Carl | NLTX | Common Stock | D | 13.0000 | -600 | -8 | 1,359,562 | ||||
| 2021-04-22 | 2021-04-21 | 4 | Walkey Carl | NLTX | Common Stock | D | 11.9800 | -1,800 | -22 | 1,360,162 | ||||
| 2021-04-16 | 2021-04-14 | 4 | Walkey Carl | NLTX | Common Stock | D | 12.2200 | -1,800 | -22 | 1,361,962 | ||||
| 2021-04-08 | 2021-04-07 | 4 | Walkey Carl | NLTX | Common Stock | D | 12.0200 | -1,800 | -22 | 1,363,762 | ||||
| 2021-04-06 | 2021-04-05 | 4 | Walkey Carl | NLTX | Common Stock | D | 13.0000 | -600 | -8 | 1,365,562 | ||||
| 2021-04-02 | 2021-03-31 | 4 | Walkey Carl | NLTX | Common Stock | D | 11.9600 | -1,800 | -22 | 1,366,162 | ||||
| 2021-03-24 | 2021-03-24 | 4 | Walkey Carl | NLTX | Common Stock | D | 11.9533 | -1,800 | -22 | 1,367,962 | ||||
| 2021-03-24 | 2021-03-22 | 4 | Walkey Carl | NLTX | Common Stock | D | 12.0000 | -600 | -7 | 1,369,762 | ||||
| 2021-03-18 | 2021-03-17 | 4 | Walkey Carl | NLTX | Common Stock | D | 11.3600 | -1,200 | -14 | 1,370,362 | ||||
| 2021-03-18 | 2021-03-17 | 4 | Ho Robert | NLTX | Common Stock | D | 11.0137 | -6,497 | -72 | 21,503 | ||||
| 2021-03-18 | 2021-03-16 | 4 | Ho Robert | NLTX | Restricted Stock Units | D | 0.00 | 25,000 | 50,000 | |||||
| 2021-03-18 | 2021-03-16 | 4 | Ho Robert | NLTX | Common Stock | D | 25,000 | 28,000 | ||||||
| 2021-03-11 | 2021-03-10 | 4 | Walkey Carl | NLTX | Common Stock | D | 11.9667 | -1,800 | -22 | 1,371,562 | ||||
| 2021-03-04 | 2021-03-03 | 4 | Walkey Carl | NLTX | Common Stock | D | 11.8667 | -1,800 | -21 | 1,373,362 | ||||
| 2021-02-25 | 2021-02-25 | 4 | Walkey Carl | NLTX | Common Stock | D | 13.0000 | -600 | -8 | 1,375,162 | ||||
| 2021-02-25 | 2021-02-24 | 4 | Walkey Carl | NLTX | Common Stock | D | 12.1400 | -1,800 | -22 | 1,375,762 | ||||
| 2021-02-18 | 2021-02-17 | 4 | Walkey Carl | NLTX | Common Stock | D | 12.7000 | -2,400 | -30 | 1,377,562 | ||||
| 2021-02-12 | 2021-02-10 | 4 | Walkey Carl | NLTX | Common Stock | D | 14.2000 | -3,000 | -43 | 1,379,962 | ||||
| 2021-02-09 | 2021-02-05 | 4 | Walkey Carl | NLTX | Common Stock | D | 14.0000 | -600 | -8 | 1,382,962 | ||||
| 2021-02-05 | 2021-02-03 | 4 | Walkey Carl | NLTX | Common Stock | D | 13.2300 | -2,400 | -32 | 1,383,562 | ||||
| 2021-02-02 | 2021-01-30 | 4 | Walkey Carl | NLTX | Stock Option (Right to Buy) | D | 12.60 | 45,000 | 45,000 | |||||
| 2021-02-02 | 3 | Walkey Carl | NLTX | Common Stock | D | 1,385,962 | ||||||||
| 2020-12-23 | 2020-07-07 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Pre-Funded Warrants | I | 518,555 | 10,283,888 | ||||||
| 2020-12-23 | 2020-07-07 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Pre-Funded Warrants | I | 38,974 | 1,199,122 | ||||||
| 2020-12-23 | 2020-07-07 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Common Stock | I | 15.2500 | 394,360 | 6,014 | 3,501,691 | ||||
| 2020-12-23 | 2020-07-07 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Common Stock | I | 15.2500 | 29,640 | 452 | 320,049 | ||||
| 2020-10-20 | 2020-10-19 | 4 | Vance Holly | NLTX | Stock Option (Right to Buy) | D | 12.30 | 220,000 | 220,000 | |||||
| 2020-09-10 | 2020-09-08 | 4 | Babler Martin | NLTX | Stock Option (Right to Buy) | D | 12.25 | 50,000 | 50,000 | |||||
| 2020-08-12 | 2020-08-10 | 4 | DRACHMAN JONATHAN G | NLTX | Stock Option (Right to Buy) | D | 12.00 | 420,000 | 420,000 | |||||
| 2020-08-12 | 2020-08-10 | 4 | Ho Robert | NLTX | Stock Option (Right to Buy) | D | 12.00 | 90,000 | 90,000 | |||||
| 2020-06-02 | 2020-06-01 | 4 | Lavelle Erin M. | NLTX | Stock Option (Right to Buy) | D | 13.58 | 50,000 | 50,000 | |||||
| 2020-05-07 | 2020-05-05 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Non-Qualified Stock Option (right to buy) | I | 12.84 | 25,000 | 25,000 | |||||
| 2020-05-07 | 2020-05-05 | 4 | Nolan Sean P. | NLTX | Stock Option (Right to Buy) | D | 12.84 | 25,000 | 25,000 | |||||
| 2020-05-07 | 2020-05-05 | 4 | Noonberg Sarah B. | NLTX | Stock Option (Right to Buy) | D | 12.84 | 25,000 | 25,000 | |||||
| 2020-05-07 | 2020-05-05 | 4 | SIMPSON TODD E | NLTX | Stock Option (Right to Buy) | D | 12.84 | 25,000 | 25,000 | |||||
| 2020-05-07 | 2020-05-05 | 4 | Williams Lewis T | NLTX | Stock Option (Right to Buy) | D | 12.84 | 25,000 | 25,000 | |||||
| 2020-04-06 | 2020-04-02 | 4 | Redmile Group, LLC | NLTX | Common Stock | I | 11.8200 | -100 | -1 | 4,041,211 | ||||
| 2020-04-06 | 2020-04-02 | 4 | Redmile Group, LLC | NLTX | Common Stock | I | 11.3039 | -9,734 | -110 | 4,041,311 | ||||
| 2020-04-06 | 2020-04-02 | 4 | Redmile Group, LLC | NLTX | Common Stock | I | 11.8506 | 1,000 | 12 | 4,051,045 | ||||
| 2020-04-06 | 2020-04-02 | 4 | Redmile Group, LLC | NLTX | Common Stock | I | 11.3605 | 38,300 | 435 | 4,050,045 | ||||
| 2020-04-06 | 2020-04-01 | 4 | Redmile Group, LLC | NLTX | Common Stock | I | 11.8650 | -200 | -2 | 4,011,745 | ||||
| 2020-04-06 | 2020-04-01 | 4 | Redmile Group, LLC | NLTX | Common Stock | I | 11.0616 | -9,634 | -107 | 4,011,945 | ||||
| 2020-04-06 | 2020-04-01 | 4 | Redmile Group, LLC | NLTX | Common Stock | I | 11.6517 | 9,000 | 105 | 4,021,579 | ||||
| 2020-04-06 | 2020-04-01 | 4 | Redmile Group, LLC | NLTX | Common Stock | I | 10.9482 | 33,500 | 367 | 4,012,579 | ||||
| 2020-04-06 | 2020-03-31 | 4 | Redmile Group, LLC | NLTX | Common Stock | I | 10.7079 | 7,500 | 80 | 3,979,079 | ||||
| 2020-04-06 | 2020-03-31 | 4 | Redmile Group, LLC | NLTX | Common Stock | I | 10.1813 | 22,500 | 229 | 3,971,579 | ||||
| 2020-04-06 | 2020-03-30 | 4 | Redmile Group, LLC | NLTX | Common Stock | I | 10.2744 | 2,700 | 28 | 3,949,079 | ||||
| 2020-04-06 | 2020-03-30 | 4 | Redmile Group, LLC | NLTX | Common Stock | I | 9.9050 | 29,800 | 295 | 3,946,379 | ||||
| 2020-04-06 | 2020-03-27 | 4 | Redmile Group, LLC | NLTX | Common Stock | I | 9.2079 | 50,000 | 460 | 3,916,579 | ||||
| 2020-04-06 | 3 | Green Jeremy | NLTX | Common Stock | I | 7,733,158 | ||||||||
| 2020-04-06 | 3 | Green Jeremy | NLTX | Common Stock | I | 7,733,158 | ||||||||
| 2020-04-06 | 3 | Green Jeremy | NLTX | Common Stock | I | 7,733,158 | ||||||||
| 2020-04-06 | 3 | Green Jeremy | NLTX | Common Stock | I | 7,733,158 | ||||||||
| 2020-03-16 | 3 | Ho Robert | NLTX | Common Stock | D | 6,000 | ||||||||
| 2020-03-16 | 3 | Ho Robert | NLTX | Common Stock | D | 6,000 | ||||||||
| 2020-03-16 | 3 | Ho Robert | NLTX | Common Stock | D | 6,000 | ||||||||
| 2020-03-16 | 2020-03-16 | 4 | Ho Robert | NLTX | Stock Option (Right to Buy) | D | 6.44 | 200,000 | 200,000 | |||||
| 2020-03-16 | 2020-03-16 | 4 | Ho Robert | NLTX | Restricted Stock Units | D | 0.00 | 75,000 | 75,000 | |||||
| 2019-12-20 | 2019-12-20 | 4 | DRACHMAN JONATHAN G | NLTX | Common Stock | D | 8.4000 | 119,047 | 1,000 | 2,198,686 | ||||
| 2019-12-20 | 2019-11-12 | 4 | DRACHMAN JONATHAN G | NLTX | Common Stock | D | 1,261,600 | 2,079,639 | ||||||
| 2019-12-20 | 2019-11-12 | 4 | DRACHMAN JONATHAN G | NLTX | Series A Preferred Stock | D | -12,616 | 0 | ||||||
| 2019-12-20 | 2019-12-20 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Pre-funded Warrants | I | 9,765,333 | 9,765,333 | ||||||
| 2019-12-20 | 2019-12-20 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Pre-funded Warrants | I | 1,160,148 | 1,161,048 | ||||||
| 2019-12-20 | 2019-12-20 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Common Stock | I | -9,765,333 | 3,107,331 | ||||||
| 2019-12-20 | 2019-12-20 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Common Stock | I | -1,160,148 | 290,409 | ||||||
| 2019-12-20 | 2019-12-20 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Common Stock | I | 8.4000 | 2,767,505 | 23,247 | 12,872,664 | ||||
| 2019-12-20 | 2019-12-20 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Common Stock | I | 8.4000 | 250,037 | 2,100 | 1,450,557 | ||||
| 2019-10-15 | 2019-10-10 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Non-Qualified Stock Option (right to buy) | I | 2.82 | 22,000 | 22,000 | |||||
| 2019-10-15 | 2019-10-10 | 4 | Williams Lewis T | NLTX | Stock Option (right to buy) | D | 2.82 | 22,000 | 22,000 | |||||
| 2019-10-15 | 2019-10-10 | 4 | Nolan Sean P. | NLTX | Stock Option (right to buy) | D | 2.82 | 22,000 | 22,000 | |||||
| 2019-10-15 | 2019-10-10 | 4 | Noonberg Sarah B. | NLTX | Stock Option (right to buy) | D | 2.82 | 22,000 | 22,000 | |||||
| 2019-10-15 | 2019-10-10 | 4 | SIMPSON TODD E | NLTX | Stock Option (right to buy) | D | 2.82 | 22,000 | 22,000 | |||||
| 2019-09-13 | 2019-08-08 | 4/A | DRACHMAN JONATHAN G | NLTX | Series A Preferred Stock | D | 12,616 | 12,616 | ||||||
| 2019-09-13 | 2019-08-08 | 4/A | DRACHMAN JONATHAN G | NLTX | Common Stock | D | 568,039 | 568,039 | ||||||
| 2019-09-11 | 2019-09-11 | 4 | DRACHMAN JONATHAN G | NLTX | Common Stock | D | 3.2975 | 136,436 | 450 | 584,428 | ||||
| 2019-09-11 | 2019-09-10 | 4 | DRACHMAN JONATHAN G | NLTX | Common Stock | D | 3.0834 | 36,742 | 113 | 447,992 | ||||
| 2019-09-11 | 2019-09-09 | 4 | DRACHMAN JONATHAN G | NLTX | Common Stock | D | 2.8450 | 76,822 | 219 | 411,250 | ||||
| 2019-09-04 | 2019-08-31 | 4 | DRACHMAN JONATHAN G | NLTX | Stock Option (Right to Buy) | D | 2.80 | 1,650,000 | 1,650,000 | |||||
| 2019-08-12 | 2019-08-08 | 4 | DRACHMAN JONATHAN G | NLTX | Series A Preferred Stock | D | 7,428 | 7,428 | ||||||
| 2019-08-12 | 2019-08-08 | 4 | DRACHMAN JONATHAN G | NLTX | Common Stock | D | 334,428 | 334,428 | ||||||
| 2019-08-08 | 2019-08-07 | 4 | BAKER BROS. ADVISORS LP See footnotes | AQXP | Common Stock | I | 3.1529 | 50,436 | 159 | 10,105,159 | ||||
| 2019-08-08 | 2019-08-07 | 4 | BAKER BROS. ADVISORS LP See footnotes | AQXP | Common Stock | I | 3.1529 | 4,564 | 14 | 1,200,520 | ||||
| 2019-08-08 | 2019-08-07 | 4 | BAKER BROS. ADVISORS LP See footnotes | AQXP | Common Stock | I | 3.0244 | 209,382 | 633 | 10,054,723 | ||||
| 2019-08-08 | 2019-08-07 | 4 | BAKER BROS. ADVISORS LP See footnotes | AQXP | Common Stock | I | 3.0244 | 18,943 | 57 | 1,195,956 | ||||
| 2019-08-08 | 2019-08-07 | 4 | BAKER BROS. ADVISORS LP See footnotes | AQXP | Common Stock | I | 2.9576 | 5,869 | 17 | 9,845,341 | ||||
| 2019-08-08 | 2019-08-07 | 4 | BAKER BROS. ADVISORS LP See footnotes | AQXP | Common Stock | I | 2.9576 | 531 | 2 | 1,177,013 | ||||
| 2019-08-08 | 2019-08-06 | 4 | BAKER BROS. ADVISORS LP See footnotes | AQXP | Common Stock | I | 2.8469 | 65,568 | 187 | 9,839,472 | ||||
| 2019-08-08 | 2019-08-06 | 4 | BAKER BROS. ADVISORS LP See footnotes | AQXP | Common Stock | I | 2.8469 | 5,932 | 17 | 1,176,482 | ||||
| 2019-08-08 | 2019-08-06 | 4 | BAKER BROS. ADVISORS LP See footnotes | AQXP | Common Stock | I | 2.8328 | 9,445 | 27 | 9,773,904 | ||||
| 2019-08-08 | 2019-08-06 | 4 | BAKER BROS. ADVISORS LP See footnotes | AQXP | Common Stock | I | 2.8328 | 855 | 2 | 1,170,550 | ||||
| 2018-08-09 | 2018-08-07 | 4 | Alam Kamran | AQXP | Stock Option (Right to Buy) | D | 3.07 | 195,000 | 195,000 | |||||
| 2018-08-09 | 2018-08-07 | 4 | MacKenzie Lloyd | AQXP | Stock Option (Right to Buy) | D | 3.07 | 145,000 | 145,000 | |||||
| 2018-08-09 | 2018-08-07 | 4 | McCloskey Shelley | AQXP | Stock Option (Right to Buy) | D | 3.07 | 75,000 | 75,000 | |||||
| 2018-08-09 | 2018-08-07 | 4 | Main David | AQXP | Stock Option (Right to Buy) | D | 3.07 | 415,000 | 415,000 | |||||
| 2018-05-16 | 2018-05-14 | 4 | LEVITT DANIEL J | AQXP | Stock Option (Right to Buy) | D | 10.56 | -3,906 | 0 | |||||
| 2018-05-16 | 2018-05-14 | 4 | LEVITT DANIEL J | AQXP | Common Stock | D | 12.6700 | -3,906 | -49 | 0 | ||||
| 2018-05-16 | 2018-05-14 | 4 | LEVITT DANIEL J | AQXP | Common Stock | D | 10.5600 | 3,906 | 41 | 3,906 | ||||
| 2018-05-09 | 2018-05-07 | 4 | Pelzer Robert | AQXP | Stock Option (Right to Buy) | D | 13.10 | 15,000 | 15,000 | |||||
| 2018-05-09 | 2018-05-07 | 4 | SIMPSON TODD E | AQXP | Stock Option (Right to Buy) | D | 13.10 | 15,000 | 15,000 | |||||
| 2018-05-09 | 2018-05-07 | 4 | LEVITT DANIEL J | AQXP | Stock Option (Right to Buy) | D | 13.10 | 15,000 | 15,000 | |||||
| 2018-05-09 | 2018-05-07 | 4 | Nolan Sean P. | AQXP | Stock Option (Right to Buy) | D | 13.10 | 15,000 | 15,000 | |||||
| 2018-05-09 | 2018-05-07 | 4 | Bridger Gary | AQXP | Stock Option (Right to Buy) | D | 13.10 | 15,000 | 15,000 | |||||
| 2018-05-09 | 2018-05-07 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Non-Qualified Stock Option (right to buy) | I | 13.10 | 30,000 | 30,000 | |||||
| 2018-03-19 | 2018-03-15 | 4 | MacKenzie Lloyd | AQXP | Stock Option (Right to Buy) | D | 10.56 | -1,302 | 0 | |||||
| 2018-03-19 | 2018-03-15 | 4 | MacKenzie Lloyd | AQXP | Common Stock | D | 14.6304 | -1,302 | -19 | 0 | ||||
| 2018-03-19 | 2018-03-15 | 4 | MacKenzie Lloyd | AQXP | Common Stock | D | 10.5600 | 1,302 | 14 | 1,302 | ||||
| 2018-03-13 | 2018-03-09 | 4 | Troupin Barbara | AQXP | Stock Option (Right to Buy) | D | 16.55 | 75,000 | 75,000 | |||||
| 2018-03-13 | 2018-03-09 | 4 | Alam Kamran | AQXP | Stock Option (Right to Buy) | D | 16.55 | 75,000 | 75,000 | |||||
| 2018-03-13 | 2018-03-09 | 4 | Jenkins Abigail | AQXP | Stock Option (Right to Buy) | D | 16.55 | 75,000 | 75,000 | |||||
| 2018-03-13 | 2018-03-09 | 4 | MacKenzie Lloyd | AQXP | Stock Option (Right to Buy) | D | 16.55 | 75,000 | 75,000 | |||||
| 2018-03-13 | 2018-03-09 | 4 | Main David | AQXP | Stock Option (Right to Buy) | D | 16.55 | 225,000 | 225,000 | |||||
| 2018-03-13 | 2018-03-09 | 4 | McCloskey Shelley | AQXP | Stock Option (Right to Buy) | D | 16.55 | 45,000 | 45,000 | |||||
| 2017-06-05 | 2017-06-05 | 4 | Main David | AQXP | Stock Option (Right to Buy) | D | 9.60 | -3,625 | 0 | |||||
| 2017-06-05 | 2017-06-05 | 4 | Main David | AQXP | Common Stock | D | 13.1575 | -3,625 | -48 | 71,530 | ||||
| 2017-06-05 | 2017-06-05 | 4 | Main David | AQXP | Common Stock | D | 9.6000 | 3,625 | 35 | 75,155 | ||||
| 2017-06-05 | 2017-06-02 | 4 | Main David | AQXP | Stock Option (Right to Buy( | D | 9.60 | -6,000 | 3,625 | |||||
| 2017-06-05 | 2017-06-02 | 4 | Main David | AQXP | Common Stock | D | 13.5933 | -6,000 | -82 | 71,530 | ||||
| 2017-06-05 | 2017-06-02 | 4 | Main David | AQXP | Common Stock | D | 9.6000 | 6,000 | 58 | 77,530 | ||||
| 2017-06-05 | 2017-06-01 | 4 | Main David | AQXP | Stock Option (Right to Buy) | D | 9.60 | -6,000 | 9,625 | |||||
| 2017-06-05 | 2017-06-01 | 4 | Main David | AQXP | Common Stock | D | 12.9980 | -6,000 | -78 | 71,530 | ||||
| 2017-06-05 | 2017-06-01 | 4 | Main David | AQXP | Common Stock | D | 9.6000 | 6,000 | 58 | 77,530 | ||||
| 2017-05-10 | 2017-05-08 | 4 | SIMPSON TODD E | AQXP | Stock Option (Right to Buy) | D | 13.74 | 9,000 | 9,000 | |||||
| 2017-05-10 | 2017-05-08 | 4 | Nolan Sean P. | AQXP | Stock Option (Right to Buy) | D | 13.74 | 9,000 | 9,000 | |||||
| 2017-05-10 | 2017-05-08 | 4 | Pelzer Robert | AQXP | Stock Option (Right to Buy) | D | 13.74 | 9,000 | 9,000 | |||||
| 2017-05-10 | 2017-05-08 | 4 | LEVITT DANIEL J | AQXP | Stock Option (Right to Buy) | D | 13.74 | 9,000 | 9,000 | |||||
| 2017-05-10 | 2017-05-08 | 4 | Bridger Gary | AQXP | Stock Option (Right to Buy) | D | 13.74 | 9,000 | 9,000 | |||||
| 2017-05-09 | 2017-05-08 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Non-Qualified Stock Option (right to buy) | I | 13.74 | 36,000 | 36,000 | |||||
| 2017-03-27 | 3 | Neu Kelvin | AQXP | Common Stock | D | 72 | ||||||||
| 2017-03-27 | 3 | Neu Kelvin | AQXP | Common Stock | D | 72 | ||||||||
| 2017-03-10 | 2017-03-08 | 4 | McCloskey Shelley | AQXP | Stock Option (Right to Buy) | D | 17.35 | 30,000 | 30,000 | |||||
| 2017-03-10 | 2017-03-08 | 4 | Mitchell David Chilton | AQXP | Stock Option (Right to Buy) | D | 17.35 | 25,000 | 25,000 | |||||
| 2017-03-10 | 2017-03-08 | 4 | Troupin Barbara | AQXP | Stock Option (Right to Buy) | D | 17.35 | 40,000 | 40,000 | |||||
| 2017-03-10 | 2017-03-08 | 4 | MacKenzie Lloyd | AQXP | Stock Option (Right to Buy) | D | 17.35 | 50,000 | 50,000 | |||||
| 2017-03-10 | 2017-03-08 | 4 | Main David | AQXP | Stock Option (Right to Buy) | D | 17.35 | 185,000 | 185,000 | |||||
| 2017-03-10 | 2017-03-08 | 4 | Alam Kamran | AQXP | Stock Option (Right to Buy) | D | 17.35 | 80,000 | 80,000 | |||||
| 2017-03-10 | 2017-03-08 | 4 | Jenkins Abigail | AQXP | Stock Option (Right to Buy) | D | 17.35 | 80,000 | 80,000 | |||||
| 2017-02-14 | 2016-01-10 | 5 | McCloskey Shelley | AQXP | Stock Option (Right to Buy) | D | 10.09 | 35,000 | 35,000 | |||||
| 2017-01-09 | 2017-01-09 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 17.7600 | 32,051 | 569 | 9,764,459 | ||||
| 2017-01-09 | 2017-01-09 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 17.7600 | 3,389 | 60 | 1,169,695 | ||||
| 2017-01-09 | 2017-01-09 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 17.5996 | 235,169 | 4,139 | 9,732,408 | ||||
| 2017-01-09 | 2017-01-09 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 17.5996 | 24,871 | 438 | 1,166,306 | ||||
| 2017-01-09 | 2017-01-09 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 16.3053 | 35,360 | 577 | 9,497,239 | ||||
| 2017-01-09 | 2017-01-09 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 16.3053 | 3,739 | 61 | 1,141,435 | ||||
| 2017-01-09 | 2017-01-09 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 15.6226 | 5,006 | 78 | 9,461,879 | ||||
| 2017-01-09 | 2017-01-09 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 15.6226 | 529 | 8 | 1,137,696 | ||||
| 2017-01-09 | 2017-01-09 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 15.1300 | 15,148 | 229 | 9,456,873 | ||||
| 2017-01-09 | 2017-01-09 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 15.1300 | 1,602 | 24 | 1,137,167 | ||||
| 2017-01-09 | 2017-01-09 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 16.1970 | 9,143 | 148 | 9,441,725 | ||||
| 2017-01-09 | 2017-01-09 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 16.1970 | 967 | 16 | 1,135,565 | ||||
| 2017-01-09 | 2017-01-09 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 15.3475 | 8,671 | 133 | 9,432,582 | ||||
| 2017-01-09 | 2017-01-09 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 15.3475 | 917 | 14 | 1,134,598 | ||||
| 2017-01-09 | 2017-01-09 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 16.8533 | 2,442 | 41 | 9,423,911 | ||||
| 2017-01-09 | 2017-01-09 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 16.8533 | 258 | 4 | 1,133,681 | ||||
| 2017-01-09 | 2017-01-09 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 15.3210 | 11,305 | 173 | 9,421,469 | ||||
| 2017-01-09 | 2017-01-09 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 15.3210 | 1,195 | 18 | 1,133,423 | ||||
| 2017-01-09 | 2017-01-09 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 16.7395 | 5,697 | 95 | 9,410,164 | ||||
| 2017-01-09 | 2017-01-09 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 16.7395 | 603 | 10 | 1,132,228 | ||||
| 2016-11-10 | 2016-11-08 | 4 | Troupin Barbara | AQXP | Stock Option (Right to Buy) | D | 11.77 | 50,000 | 50,000 | |||||
| 2016-10-06 | 3 | Troupin Barbara | AQXP | No securities are benefically owned | D | 0 | ||||||||
| 2016-09-21 | 2016-09-20 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 13.1497 | 12,550 | 165 | 1,131,625 | ||||
| 2016-09-21 | 2016-09-20 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 12.2500 | 2,476,348 | 30,335 | 9,404,467 | ||||
| 2016-09-21 | 2016-09-20 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 12.2500 | 294,707 | 3,610 | 1,119,075 | ||||
| 2016-08-05 | 2016-08-03 | 4 | Jenkins Abigail | AQXP | Stock Option (Right to Buy) | D | 8.97 | 50,000 | 50,000 | |||||
| 2016-06-15 | 3 | Jenkins Abigail | AQXP | No securities are beneficially owned | D | 0 | ||||||||
| 2016-05-11 | 2016-05-09 | 4 | LEVITT DANIEL J | AQXP | Stock Option (Right to Buy) | D | 7.73 | 7,500 | 7,500 | |||||
| 2016-05-11 | 2016-05-09 | 4 | SIMPSON TODD E | AQXP | Stock Option (Right to Buy) | D | 7.73 | 7,500 | 7,500 | |||||
| 2016-05-11 | 2016-05-09 | 4 | Pelzer Robert | AQXP | Stock Option (Right to Buy) | D | 7.73 | 7,500 | 7,500 | |||||
| 2016-05-11 | 2016-05-09 | 4 | Nolan Sean P. | AQXP | Stock Option (Right to Buy) | D | 7.73 | 7,500 | 7,500 | |||||
| 2016-05-11 | 2016-05-09 | 4 | Bridger Gary | AQXP | Stock Option (Right to Buy) | D | 7.73 | 7,500 | 7,500 | |||||
| 2016-03-16 | 2016-03-16 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8.1560 | 128,975 | 1,052 | 6,928,119 | ||||
| 2016-03-16 | 2016-03-16 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8.1560 | 14,046 | 115 | 824,368 | ||||
| 2016-03-16 | 2016-03-16 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 7.9084 | 185,413 | 1,466 | 6,799,144 | ||||
| 2016-03-16 | 2016-03-16 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 7.9084 | 20,192 | 160 | 810,322 | ||||
| 2016-03-16 | 2016-03-16 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 7.6993 | 11,840 | 91 | 6,613,731 | ||||
| 2016-03-16 | 2016-03-16 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 7.6993 | 1,289 | 10 | 790,130 | ||||
| 2016-03-16 | 2016-03-15 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8.0257 | 68,132 | 547 | 6,601,891 | ||||
| 2016-03-16 | 2016-03-15 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8.0257 | 7,420 | 60 | 788,841 | ||||
| 2016-03-16 | 2016-03-15 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 7.8786 | 30,986 | 244 | 6,533,759 | ||||
| 2016-03-16 | 2016-03-15 | 4 | BAKER BROS. ADVISORS LP | AQXP | Common Stock | I | 7.8786 | 3,374 | 27 | 781,421 | ||||
| 2016-03-14 | 2016-03-10 | 4 | SHREWSBURY STEPHEN B | AQXP | Stock Option (Right to Buy) | D | 8.08 | 35,000 | 35,000 | |||||
| 2016-03-14 | 2016-03-10 | 4 | Main David | AQXP | Stock Option (Right to Buy) | D | 8.08 | 120,000 | 120,000 | |||||
| 2016-03-14 | 2016-03-10 | 4 | Alam Kamran | AQXP | Stock Option (Right to Buy) | D | 8.08 | 40,000 | 40,000 | |||||
| 2016-03-14 | 2016-03-10 | 4 | MacKenzie Lloyd | AQXP | Stock Option (Right to Buy) | D | 8.08 | 35,000 | 35,000 | |||||
| 2016-03-14 | 2016-03-10 | 4 | Mitchell David Chilton | AQXP | Stock Option (Right to Buy) | D | 8.08 | 25,000 | 25,000 | |||||
| 2016-01-26 | 2016-01-26 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 10.9960 | 3,581 | 39 | 6,502,773 | ||||
| 2016-01-26 | 2016-01-26 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 10.9960 | 395 | 4 | 778,047 | ||||
| 2016-01-26 | 2016-01-26 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 10.8033 | 66,345 | 717 | 6,499,192 | ||||
| 2016-01-26 | 2016-01-26 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 10.8033 | 7,318 | 79 | 777,652 | ||||
| 2016-01-26 | 2016-01-25 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 11.2043 | 2,522 | 28 | 6,432,847 | ||||
| 2016-01-26 | 2016-01-25 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 11.2043 | 278 | 3 | 770,334 | ||||
| 2016-01-26 | 2016-01-25 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 10.9755 | 4,503 | 49 | 6,430,325 | ||||
| 2016-01-26 | 2016-01-25 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 10.9755 | 497 | 5 | 770,056 | ||||
| 2016-01-26 | 2016-01-25 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 11.2326 | 2,833 | 32 | 6,425,822 | ||||
| 2016-01-26 | 2016-01-25 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 11.2326 | 312 | 4 | 769,559 | ||||
| 2016-01-26 | 2016-01-22 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 10.6908 | 25,650 | 274 | 6,422,989 | ||||
| 2016-01-26 | 2016-01-22 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 10.6908 | 2,810 | 30 | 769,247 | ||||
| 2016-01-26 | 2016-01-22 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 10.6000 | 156 | 2 | 6,397,339 | ||||
| 2016-01-26 | 2016-01-22 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 10.6000 | 17 | 0 | 766,437 | ||||
| 2016-01-26 | 2016-01-22 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 10.6937 | 4,021 | 43 | 6,397,183 | ||||
| 2016-01-26 | 2016-01-22 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 10.6937 | 440 | 5 | 766,420 | ||||
| 2016-01-26 | 2016-01-22 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 10.7814 | 17,221 | 186 | 6,393,162 | ||||
| 2016-01-26 | 2016-01-22 | 4 | BAKER BROS. ADVISORS LP | AQXP | Common Stock | I | 10.7814 | 1,887 | 20 | 765,980 | ||||
| 2016-01-20 | 2016-01-20 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8.9000 | 1,734 | 15 | 6,375,941 | ||||
| 2016-01-20 | 2016-01-20 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8.9000 | 190 | 2 | 764,093 | ||||
| 2016-01-20 | 2016-01-20 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8.9572 | 27,996 | 251 | 6,374,207 | ||||
| 2016-01-20 | 2016-01-20 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8.9572 | 3,067 | 27 | 763,903 | ||||
| 2016-01-20 | 2016-01-20 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8.9559 | 13,789 | 123 | 6,346,211 | ||||
| 2016-01-20 | 2016-01-20 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8.9559 | 1,511 | 14 | 760,836 | ||||
| 2016-01-20 | 2016-01-20 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 9.8852 | 57,453 | 568 | 6,332,422 | ||||
| 2016-01-20 | 2016-01-20 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 9.8852 | 6,294 | 62 | 759,325 | ||||
| 2016-01-20 | 2016-01-19 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 9.1537 | 14,313 | 131 | 6,274,969 | ||||
| 2016-01-20 | 2016-01-19 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 9.1537 | 1,568 | 14 | 753,031 | ||||
| 2016-01-20 | 2016-01-19 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 9.2149 | 10,123 | 93 | 6,260,656 | ||||
| 2016-01-20 | 2016-01-19 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 9.2149 | 1,109 | 10 | 751,463 | ||||
| 2016-01-20 | 2016-01-19 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 9.0757 | 45,903 | 417 | 6,250,533 | ||||
| 2016-01-20 | 2016-01-19 | 4 | BAKER BROS. ADVISORS LP | AQXP | Common Stock | I | 9.0757 | 5,029 | 46 | 750,354 | ||||
| 2016-01-15 | 2016-01-15 | 4/A | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8.5591 | 47,193 | 404 | 6,204,630 | ||||
| 2016-01-15 | 2016-01-15 | 4/A | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8.5591 | 5,196 | 44 | 745,325 | ||||
| 2016-01-15 | 2016-01-15 | 4/A | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8.9529 | 4,949 | 44 | 6,157,437 | ||||
| 2016-01-15 | 2016-01-15 | 4/A | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8.9529 | 545 | 5 | 740,129 | ||||
| 2016-01-15 | 2016-01-15 | 4/A | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8.8249 | 3,279 | 29 | 6,152,488 | ||||
| 2016-01-15 | 2016-01-15 | 4/A | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8.8249 | 361 | 3 | 739,584 | ||||
| 2016-01-15 | 2016-01-15 | 4/A | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8.0999 | 20,851 | 169 | 6,149,209 | ||||
| 2016-01-15 | 2016-01-15 | 4/A | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8.0999 | 2,296 | 19 | 739,223 | ||||
| 2016-01-15 | 2016-01-14 | 4/A | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8.0764 | 2,998 | 24 | 6,128,358 | ||||
| 2016-01-15 | 2016-01-14 | 4/A | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8.0764 | 330 | 3 | 736,927 | ||||
| 2016-01-15 | 2016-01-14 | 4/A | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 7.9110 | 12,706 | 101 | 6,125,360 | ||||
| 2016-01-15 | 2016-01-14 | 4/A | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 7.9110 | 1,399 | 11 | 736,597 | ||||
| 2016-01-15 | 2016-01-14 | 4/A | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8.1717 | 90,550 | 740 | 6,112,654 | ||||
| 2016-01-15 | 2016-01-14 | 4/A | BAKER BROS. ADVISORS LP | AQXP | Common Stock | I | 8.1717 | 9,970 | 81 | 735,198 | ||||
| 2016-01-15 | 2016-01-15 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8.5591 | 47,193 | 404 | 6,204,630 | ||||
| 2016-01-15 | 2016-01-15 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8.5591 | 5,196 | 44 | 745,325 | ||||
| 2016-01-15 | 2016-01-15 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8.9529 | 4,949 | 44 | 6,157,437 | ||||
| 2016-01-15 | 2016-01-15 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8.9529 | 545 | 5 | 740,129 | ||||
| 2016-01-15 | 2016-01-15 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8.8249 | 3,279 | 29 | 6,152,488 | ||||
| 2016-01-15 | 2016-01-15 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8.8249 | 361 | 3 | 739,584 | ||||
| 2016-01-15 | 2016-01-15 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8.0999 | 20,851 | 169 | 6,149,209 | ||||
| 2016-01-15 | 2016-01-15 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8.0999 | 2,296 | 19 | 739,223 | ||||
| 2016-01-15 | 2016-01-14 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8.0764 | 2,998 | 24 | 6,128,358 | ||||
| 2016-01-15 | 2016-01-14 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8.0764 | 330 | 3 | 736,927 | ||||
| 2016-01-15 | 2016-01-14 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 7.9110 | 12,706 | 101 | 6,125,360 | ||||
| 2016-01-15 | 2016-01-14 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 7.9110 | 1,399 | 11 | 736,597 | ||||
| 2016-01-15 | 2016-01-14 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8.1717 | 90,550 | 740 | 6,112,654 | ||||
| 2016-01-15 | 2016-01-14 | 4 | BAKER BROS. ADVISORS LP | AQXP | Common Stock | I | 8.1717 | 9,970 | 81 | 735,198 | ||||
| 2015-12-23 | 3 | McCloskey Shelley | AQXP | No securities are beneficially owned | D | 0 | ||||||||
| 2015-11-03 | 2015-10-31 | 4 | Bridger Gary | AQXP | Common Stock | I | -1,543,989 | 0 | ||||||
| 2015-09-11 | 2015-09-10 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 15.5000 | 2,213,469 | 34,309 | 6,022,104 | ||||
| 2015-09-11 | 2015-09-10 | 4 | BAKER BROS. ADVISORS LP | AQXP | Common Stock | I | 15.5000 | 266,563 | 4,132 | 725,228 | ||||
| 2015-08-26 | 2015-08-24 | 4 | Mitchell David Chilton By spouse | AQXP | Common Stock | I | 17.8100 | 3,575 | 64 | 3,575 | ||||
| 2015-08-14 | 2015-08-12 | 4 | MacKenzie Lloyd | AQXP | Stock Option (Right to Buy) | D | 5.76 | 28,075 | 1,872 | |||||
| 2015-08-14 | 2015-08-12 | 4 | MacKenzie Lloyd | AQXP | Stock Option (Right to Buy) | D | 5.76 | 7,812 | 0 | |||||
| 2015-08-14 | 2015-08-12 | 4 | MacKenzie Lloyd | AQXP | Common Stock | D | 18.6700 | -35,887 | -670 | 0 | ||||
| 2015-08-14 | 2015-08-12 | 4 | MacKenzie Lloyd | AQXP | Common Stock | D | 5.7600 | 28,075 | 162 | 35,887 | ||||
| 2015-08-14 | 2015-08-12 | 4 | MacKenzie Lloyd | AQXP | Common Stock | D | 5.7600 | 7,812 | 45 | 7,812 | ||||
| 2015-08-14 | 2015-08-12 | 4 | Alam Kamran | AQXP | Stock Option (Right to Buy) | D | 5.76 | -20,833 | 0 | |||||
| 2015-08-14 | 2015-08-12 | 4 | Alam Kamran | AQXP | Stock Option (Right to Buy) | D | 5.76 | -8,246 | 2,170 | |||||
| 2015-08-14 | 2015-08-12 | 4 | Alam Kamran | AQXP | Common Stock | D | 18.6700 | -29,079 | -543 | 0 | ||||
| 2015-08-14 | 2015-08-12 | 4 | Alam Kamran | AQXP | Common Stock | D | 5.7600 | 20,833 | 120 | 29,079 | ||||
| 2015-08-14 | 2015-08-12 | 4 | Alam Kamran | AQXP | Common Stock | D | 5.7600 | 8,246 | 47 | 8,246 | ||||
| 2015-08-13 | 2015-08-11 | 4 | Mitchell David Chilton | AQXP | Common Stock | D | 24.3600 | 1,600 | 39 | 1,600 | ||||
| 2015-08-12 | 2015-08-10 | 4 | PFIZER INC | AQXP | Common Stock | D | 23.4112 | -58,632 | -1,373 | 975,403 | ||||
| 2015-08-12 | 2015-08-10 | 4 | PFIZER INC | AQXP | Common Stock | D | 22.5994 | -44,268 | -1,000 | 1,034,035 | ||||
| 2015-08-12 | 2015-08-10 | 4 | PFIZER INC | AQXP | Common Stock | D | 24.3129 | -31,400 | -763 | 1,078,303 | ||||
| 2015-08-12 | 2015-08-10 | 4 | PFIZER INC | AQXP | Common Stock | D | 20.3476 | -25,931 | -528 | 1,109,703 | ||||
| 2015-08-12 | 2015-08-10 | 4 | PFIZER INC | AQXP | Common Stock | D | 26.3213 | -13,109 | -345 | 1,135,634 | ||||
| 2015-08-12 | 2015-08-10 | 4 | PFIZER INC | AQXP | Common Stock | D | 25.3233 | -12,726 | -322 | 1,148,743 | ||||
| 2015-08-12 | 2015-08-10 | 4 | PFIZER INC | AQXP | Common Stock | D | 38.4947 | -11,627 | -448 | 1,161,469 | ||||
| 2015-08-12 | 2015-08-10 | 4 | PFIZER INC | AQXP | Common Stock | D | 36.3687 | -10,544 | -383 | 1,173,096 | ||||
| 2015-08-12 | 2015-08-10 | 4 | PFIZER INC | AQXP | Common Stock | D | 37.2264 | -9,901 | -369 | 1,183,640 | ||||
| 2015-08-12 | 2015-08-10 | 4 | PFIZER INC | AQXP | Common Stock | D | 39.5172 | -9,142 | -361 | 1,193,541 | ||||
| 2015-08-12 | 2015-08-10 | 4 | PFIZER INC | AQXP | Common Stock | D | 21.4506 | -8,969 | -192 | 1,202,683 | ||||
| 2015-08-12 | 2015-08-10 | 4 | PFIZER INC | AQXP | Common Stock | D | 27.3561 | -8,565 | -234 | 1,211,652 | ||||
| 2015-08-12 | 2015-08-10 | 4 | PFIZER INC | AQXP | Common Stock | D | 40.2955 | -6,073 | -245 | 1,220,217 | ||||
| 2015-08-12 | 2015-08-10 | 4 | PFIZER INC | AQXP | Common Stock | D | 35.6072 | -3,207 | -114 | 1,226,290 | ||||
| 2015-08-12 | 2015-08-10 | 4 | PFIZER INC | AQXP | Common Stock | D | 28.4670 | -2,975 | -85 | 1,229,497 | ||||
| 2015-08-12 | 2015-08-10 | 4 | PFIZER INC | AQXP | Common Stock | D | 41.2475 | -2,840 | -117 | 1,232,472 | ||||
| 2015-08-12 | 2015-08-10 | 4 | PFIZER INC | AQXP | Common Stock | D | 29.0000 | -18 | -1 | 1,235,312 | ||||
| 2015-08-12 | 2015-08-11 | 4 | JOHNSON & JOHNSON Johnson & Johnson Innovation - JJDC, Inc. | AQXP | Common Stock | I | 20.7400 | -1,283,366 | -26,617 | 100,000 | ||||
| 2015-08-12 | 2015-08-10 | 4 | JOHNSON & JOHNSON Johnson & Johnson Innovation - JJDC, Inc. | AQXP | Common Stock | I | 31.6600 | -231,455 | -7,328 | 1,383,366 | ||||
| 2015-08-10 | 3/A | BAKER FELIX | AQXP | Common Stock | D | 2,260 | ||||||||
| 2015-08-10 | 3/A | BAKER FELIX | AQXP | Common Stock | D | 2,260 | ||||||||
| 2015-08-10 | 3 | 667, L.P. | AQXP | Common Stock | I | 8,075,935 | ||||||||
| 2015-08-10 | 3 | 667, L.P. | AQXP | Common Stock | I | 4,725,965 | ||||||||
| 2015-08-10 | 3 | 667, L.P. | AQXP | Common Stock | I | 8,075,935 | ||||||||
| 2015-08-10 | 3 | 667, L.P. | AQXP | Common Stock | I | 8,075,935 | ||||||||
| 2015-08-10 | 3 | 667, L.P. | AQXP | Common Stock | I | 4,725,965 | ||||||||
| 2015-08-10 | 3 | 667, L.P. | AQXP | Common Stock | I | 4,725,965 | ||||||||
| 2015-08-10 | 3 | 667, L.P. | AQXP | Common Stock | I | 4,725,965 | ||||||||
| 2015-08-10 | 3 | 667, L.P. | AQXP | Common Stock | I | 8,075,935 | ||||||||
| 2015-08-10 | 3 | 667, L.P. | AQXP | Common Stock | I | 4,725,965 | ||||||||
| 2015-08-10 | 3 | 667, L.P. | AQXP | Common Stock | I | 8,075,935 | ||||||||
| 2015-08-10 | 3 | 667, L.P. | AQXP | Common Stock | I | 4,725,965 | ||||||||
| 2015-08-10 | 3 | 667, L.P. | AQXP | Common Stock | I | 4,725,965 | ||||||||
| 2015-08-10 | 3 | 667, L.P. | AQXP | Common Stock | I | 8,075,935 | ||||||||
| 2015-08-10 | 3 | 667, L.P. | AQXP | Common Stock | I | 8,075,935 | ||||||||
| 2015-03-16 | 2015-03-12 | 4 | SHREWSBURY STEPHEN B | AQXP | Stock Option (Right to Buy) | D | 12.03 | 25,000 | 25,000 | |||||
| 2015-03-16 | 2015-03-12 | 4 | Nolan Sean P. | AQXP | Stock Option (Right to Buy) | D | 12.03 | 10,000 | 10,000 | |||||
| 2015-03-16 | 2015-03-12 | 4 | Main David | AQXP | Stock Option (Right to Buy) | D | 12.03 | 65,000 | 65,000 | |||||
| 2015-03-16 | 2015-03-12 | 4 | Pelzer Robert | AQXP | Stock Option (Right to Buy) | D | 12.03 | 5,000 | 5,000 | |||||
| 2015-03-16 | 2015-03-12 | 4 | SIMPSON TODD E | AQXP | Stock Option (Right to Buy) | D | 12.03 | 5,000 | 5,000 | |||||
| 2015-03-16 | 2015-03-12 | 4 | MacKenzie Lloyd | AQXP | Stock Option (Right to Buy) | D | 12.03 | 25,000 | 25,000 | |||||
| 2015-03-16 | 2015-03-12 | 4 | LEVITT DANIEL J | AQXP | Stock Option (Right to Buy) | D | 12.03 | 5,000 | 5,000 | |||||
| 2015-03-16 | 2015-03-12 | 4 | Bridger Gary | AQXP | Stock Option (Right to Buy) | D | 12.03 | 5,000 | 5,000 | |||||
| 2015-03-16 | 2015-03-12 | 4 | Alam Kamran | AQXP | Stock Option (Right to Buy) | D | 12.03 | 25,000 | 25,000 | |||||
| 2015-02-09 | 2014-09-02 | 5 | SHREWSBURY STEPHEN B | AQXP | Common Stock | D | 8.2200 | 400 | 3 | 400 | ||||
| 2015-02-03 | 2014-03-12 | 4/A | JOHNSON & JOHNSON By Johnson & Johnson Development Corporation | AQXP | Series C Preferred Stock | I | -379,543 | 0 | ||||||
| 2015-02-03 | 2014-03-12 | 4/A | JOHNSON & JOHNSON By Johnson & Johnson Development Corporation | AQXP | Series B-2 Preferred Stock | I | -292,532 | 0 | ||||||
| 2015-02-03 | 2014-03-12 | 4/A | JOHNSON & JOHNSON By Johnson & Johnson Development Corporation | AQXP | Series B-1 Preferred Stock | I | -293,884 | 0 | ||||||
| 2015-02-03 | 2014-03-12 | 4/A | JOHNSON & JOHNSON By Johnson & Johnson Development Corporation | AQXP | Series A-2 Preferred Stock | I | -170,454 | 0 | ||||||
| 2015-02-03 | 2014-03-12 | 4/A | JOHNSON & JOHNSON By Johnson & Johnson Development Corporation | AQXP | Series A-1 Preferred Stock | I | -255,681 | 0 | ||||||
| 2015-02-03 | 2014-03-12 | 4/A | JOHNSON & JOHNSON Johnson & Johnson Development Corporation | AQXP | Common Stock | I | 11.0000 | 272,727 | 3,000 | 1,664,821 | ||||
| 2015-02-03 | 2014-03-12 | 4/A | JOHNSON & JOHNSON Johnson & Johnson Development Corporation | AQXP | Common Stock | I | 1,392,094 | 1,392,094 | ||||||
| 2015-01-13 | 2015-01-11 | 4 | Mitchell David Chilton | AQXP | Stock Option (Right to Buy) | D | 9.51 | 35,000 | 35,000 | |||||
| 2014-12-18 | 2014-12-17 | 4 | JOHNSON & JOHNSON Johnson & Johnson Development Corporation | AQXP | Common Stock | I | 7.5800 | -1,593 | -12 | 1,342,094 | ||||
| 2014-12-18 | 2014-12-16 | 4 | JOHNSON & JOHNSON Johnson & Johnson Development Corporation | AQXP | Common Stock | I | 7.6300 | -6,507 | -50 | 1,343,687 | ||||
| 2014-12-15 | 2014-12-12 | 4 | JOHNSON & JOHNSON Johnson & Johnson Development Corporation | AQXP | Common Stock | I | 7.5100 | -3,645 | -27 | 1,350,194 | ||||
| 2014-12-15 | 2014-12-11 | 4 | JOHNSON & JOHNSON Johnson & Johnson Development Corporation | AQXP | Common Stock | I | 7.5000 | -1,355 | -10 | 1,353,839 | ||||
| 2014-12-10 | 2014-12-10 | 4 | JOHNSON & JOHNSON Johnson & Johnson Development Corporation | AQXP | Common Stock | I | 7.7000 | -1,300 | -10 | 1,355,194 | ||||
| 2014-12-10 | 2014-12-09 | 4 | JOHNSON & JOHNSON Johnson & Johnson Development Corporation | AQXP | Common Stock | I | 7.7300 | -5,000 | -39 | 1,356,494 | ||||
| 2014-12-10 | 2014-12-08 | 4 | JOHNSON & JOHNSON Johnson & Johnson Development Corporation | AQXP | Common Stock | I | 7.6900 | -2,000 | -15 | 1,361,494 | ||||
| 2014-12-05 | 2014-12-05 | 4 | JOHNSON & JOHNSON Johnson & Johnson Development Corporation | AQXP | Common Stock | I | 7.7800 | -4,200 | -33 | 1,363,494 | ||||
| 2014-12-05 | 2014-12-04 | 4 | JOHNSON & JOHNSON Johnson & Johnson Development Corporation | AQXP | Common Stock | I | 7.7600 | -10,073 | -78 | 1,367,694 | ||||
| 2014-12-05 | 2014-12-03 | 4 | JOHNSON & JOHNSON Johnson & Johnson Development Corporation | AQXP | Common Stock | I | 7.7500 | -1,627 | -13 | 1,377,767 | ||||
| 2014-12-03 | 2014-12-01 | 4 | JOHNSON & JOHNSON Johnson & Johnson Development Corporation | AQXP | Common Stock | I | 7.5400 | -1,200 | -9 | 1,379,394 | ||||
| 2014-11-26 | 2014-11-26 | 4 | JOHNSON & JOHNSON Johnson & Johnson Development Corporation | AQXP | Common Stock | I | 7.6000 | -500 | -4 | 1,380,594 | ||||
| 2014-11-26 | 2014-11-25 | 4 | JOHNSON & JOHNSON Johnson & Johnson Development Corporation | AQXP | Common Stock | I | 7.8000 | -1,500 | -12 | 1,381,094 | ||||
| 2014-11-24 | 2014-11-24 | 4 | JOHNSON & JOHNSON Johnson & Johnson Development Corporation | AQXP | Common Stock | I | 8.0200 | -4,000 | -32 | 1,382,594 | ||||
| 2014-11-24 | 2014-11-21 | 4 | JOHNSON & JOHNSON Johnson & Johnson Development Corporation | AQXP | Common Stock | I | 8.2500 | -2,400 | -20 | 1,386,594 | ||||
| 2014-11-24 | 2014-11-20 | 4 | JOHNSON & JOHNSON Johnson & Johnson Development Corporation | AQXP | Common Stock | I | 8.2100 | -3,100 | -25 | 1,388,994 | ||||
| 2014-05-12 | 2014-05-08 | 4 | SHREWSBURY STEPHEN B | AQXP | Stock Option (Right to Buy) | D | 10.10 | 31,250 | 31,250 | |||||
| 2014-05-12 | 2014-05-08 | 4 | Main David | AQXP | Stock Option (Right to Buy) | D | 10.10 | 65,000 | 65,000 | |||||
| 2014-05-12 | 2014-05-08 | 4 | Alam Kamran | AQXP | Stock Option (Right to Buy) | D | 10.10 | 31,250 | 31,250 | |||||
| 2014-05-12 | 2014-05-08 | 4 | MacKenzie Lloyd | AQXP | Stock Option (Right to Buy) | D | 10.10 | 25,000 | 25,000 | |||||
| 2014-03-14 | 2014-03-12 | 4 | Main David | AQXP | Common Exchangeable Shares | D | -71,530 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Main David | AQXP | Common Exchangeable Shares | D | 11.0000 | -9,459 | -104 | 0 | ||||
| 2014-03-14 | 2014-03-12 | 4 | Main David | AQXP | Common Stock | D | 71,530 | 71,530 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Main David | AQXP | Common Special Voting Stock | D | -71,530 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Main David | AQXP | Common Special Voting Stock | D | 11.0000 | -9,459 | -104 | 71,530 | ||||
| 2014-03-14 | 2014-03-12 | 4 | Ventures West 8 Limited Partnership | AQXP | Series C Exchangeable Shares | D | -378,786 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Ventures West 8 Limited Partnership | AQXP | Series C Preferred Stock | D | -378,786 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Ventures West 8 Limited Partnership | AQXP | Series C Preferred Stock | D | 378,786 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Ventures West 8 Limited Partnership | AQXP | Series B-2 Exchangeable Shares | D | -325,035 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Ventures West 8 Limited Partnership | AQXP | Series B-2 Preferred Stock | D | -325,035 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Ventures West 8 Limited Partnership | AQXP | Series B-2 Preferred Stock | D | 325,035 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Ventures West 8 Limited Partnership | AQXP | Series B-1 Exchangeable Shares | D | -326,538 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Ventures West 8 Limited Partnership | AQXP | Series B-1 Preferred Stock | D | -326,538 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Ventures West 8 Limited Partnership | AQXP | Series B-1 Preferred Stock | D | 326,538 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Ventures West 8 Limited Partnership | AQXP | Series A-2 Preferred Stock | D | -189,393 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Ventures West 8 Limited Partnership | AQXP | Series A-2 Exchangeable Shares | D | -189,393 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Ventures West 8 Limited Partnership | AQXP | Series A-2 Preferred Stock | D | 189,393 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Ventures West 8 Limited Partnership | AQXP | Series A-1 Exchangeable Shares | D | -284,090 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Ventures West 8 Limited Partnership | AQXP | Series A-1 Preferred Stock | D | -284,090 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Ventures West 8 Limited Partnership | AQXP | Series A-1 Preferred Stock | D | 284,090 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Ventures West 8 Limited Partnership | AQXP | Common Exchangeable Shares | D | -40,147 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Ventures West 8 Limited Partnership | AQXP | Common Exchangeable Shares | D | 11.0000 | 36,502 | 402 | 40,147 | ||||
| 2014-03-14 | 2014-03-12 | 4 | Ventures West 8 Limited Partnership | AQXP | Common Stock | D | 1,543,989 | 1,543,989 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Ventures West 8 Limited Partnership | AQXP | Series C Special Voting Stock | D | -378,786 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Ventures West 8 Limited Partnership | AQXP | Series B-2 Special Voting Stock | D | -325,035 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Ventures West 8 Limited Partnership | AQXP | Series B-1 Special Voting Stock | D | -326,538 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Ventures West 8 Limited Partnership | AQXP | Series A-2 Special Voting Stock | D | -189,393 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Ventures West 8 Limited Partnership | AQXP | Series A-1 Special Voting Stock | D | -284,090 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Ventures West 8 Limited Partnership | AQXP | Common Special Voting Stock | D | -40,147 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Ventures West 8 Limited Partnership | AQXP | Common Special Voting Stock | D | 36,502 | 40,147 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Bridger Gary See Note | AQXP | Series C Preferred Stock | I | -378,786 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Bridger Gary See Note | AQXP | Series C Exchangeable Shares | I | -378,786 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Bridger Gary See Note | AQXP | Series C Preferred Stock | I | 378,786 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Bridger Gary See Note | AQXP | Series B-2 Preferred Stock | I | -325,035 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Bridger Gary See Note | AQXP | Series B-2 Exchangeable Shares | I | -325,035 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Bridger Gary See Note | AQXP | Series B-2 Preferred Stock | I | 325,035 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Bridger Gary See Note | AQXP | Series B-1 Preferred Stock | I | -326,538 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Bridger Gary See Note | AQXP | Series B-1 Exchangeable Shares | I | -326,538 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Bridger Gary See Note | AQXP | Series B-1 Preferred Stock | I | 326,538 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Bridger Gary See Note | AQXP | Series A-2 Preferred Stock | I | -189,393 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Bridger Gary See Note | AQXP | Series A-2 Exchangeable Shares | I | -189,393 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Bridger Gary See Note | AQXP | Series A-2 Preferred Stock | I | 189,393 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Bridger Gary See Note | AQXP | Series A-1 Exchangeable Shares | I | -284,090 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Bridger Gary See Note | AQXP | Series A-1 Preferred Stock | I | -284,090 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Bridger Gary See Note | AQXP | Series A-1 Preferred Stock | I | 284,090 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Bridger Gary See Note | AQXP | Common Exchangeable Shares | I | -40,147 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Bridger Gary See Note | AQXP | Common Exchangeable Shares | I | 11.0000 | 36,502 | 402 | 40,147 | ||||
| 2014-03-14 | 2014-03-12 | 4 | Bridger Gary See Note | AQXP | Common Stock | I | 1,543,989 | 1,543,989 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Bridger Gary See Note | AQXP | Series C Special Voting Stock | I | -378,786 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Bridger Gary See Note | AQXP | Series B-2 Special Voting Stock | I | -325,035 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Bridger Gary See Note | AQXP | Series B-1 Special Voting Stock | I | -326,538 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Bridger Gary See Note | AQXP | Series A-2 Special Voting Stock | I | -189,393 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Bridger Gary See Note | AQXP | Series A-1 Special Voting Stock | I | -284,090 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Bridger Gary See Note | AQXP | Common Special Voting Stock | I | -40,147 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Bridger Gary See Note | AQXP | Common Special Voting Stock | I | 36,502 | 40,147 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | PFIZER INC | AQXP | Series C Preferred Stock | D | -301,005 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | PFIZER INC | AQXP | Series B-2 Preferred Stock | D | -327,178 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | PFIZER INC | AQXP | Series B-1 Preferred Stock | D | -334,420 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | PFIZER INC | AQXP | Common Stock | D | 11.0000 | 272,727 | 3,000 | 1,235,330 | ||||
| 2014-03-14 | 2014-03-12 | 4 | PFIZER INC | AQXP | Common Stock | D | 962,603 | 962,603 | ||||||
| 2014-03-12 | 2014-03-12 | 4 | JOHNSON & JOHNSON By Johnson & Johnson Development Corporation | AQXP | Series C Preferred Stock | I | -379,543 | 0 | ||||||
| 2014-03-12 | 2014-03-12 | 4 | JOHNSON & JOHNSON By Johnson & Johnson Development Corporation | AQXP | Series B-2 Preferred Stock | I | -292,532 | 0 | ||||||
| 2014-03-12 | 2014-03-12 | 4 | JOHNSON & JOHNSON By Johnson & Johnson Development Corporation | AQXP | Series B-1 Preferred Stock | I | -293,884 | 0 | ||||||
| 2014-03-12 | 2014-03-12 | 4 | JOHNSON & JOHNSON By Johnson & Johnson Development Corporation | AQXP | Series A-2 Preferred Stock | I | -170,454 | 0 | ||||||
| 2014-03-12 | 2014-03-12 | 4 | JOHNSON & JOHNSON By Johnson & Johnson Development Corporation | AQXP | Series A-1 Preferred Stock | I | -255,681 | 0 | ||||||
| 2014-03-12 | 2014-03-12 | 4 | JOHNSON & JOHNSON Johnson & Johnson Development Corporation | AQXP | Common Stock | I | 1,392,094 | 1,392,094 | ||||||
| 2014-03-10 | 2014-03-06 | 4 | SIMPSON TODD E | AQXP | Stock Option (Right to Buy) | D | 11.00 | 8,333 | 8,333 | |||||
| 2014-03-10 | 2014-03-06 | 4 | Pelzer Robert | AQXP | Stock Option (Right to Buy) | D | 11.00 | 8,333 | 14,843 | |||||
| 2014-03-10 | 2014-03-06 | 4 | LEVITT DANIEL J | AQXP | Stock Option (Right to Buy) | D | 11.00 | 8,333 | 20,051 | |||||
| 2014-03-10 | 2014-03-06 | 4 | Bridger Gary | AQXP | Stock Option (Right to Buy) | D | 11.00 | 8,333 | 8,333 | |||||
| 2014-03-06 | 3 | Jones Elaine V | AQXP | No securities are beneficially owned | D | 0 | ||||||||
| 2014-03-06 | 3 | SIMPSON TODD E | AQXP | No securities are beneficially owned | D | 0 | ||||||||
| 2014-03-06 | 3 | Main David | AQXP | Common Special Voting Stock | D | 161,978 | ||||||||
| 2014-03-06 | 3 | Main David | AQXP | Common Special Voting Stock | D | 161,978 | ||||||||
| 2014-03-06 | 3 | Ventures West 8 Limited Partnership | AQXP | Common Special Voting Stock | D | 1,511,132 | ||||||||
| 2014-03-06 | 3 | Ventures West 8 Limited Partnership | AQXP | Series A- Special Voting Stock | D | 1,791,577 | ||||||||
| 2014-03-06 | 3 | Ventures West 8 Limited Partnership | AQXP | Series A-2 Special Voting Stock | D | 1,696,880 | ||||||||
| 2014-03-06 | 3 | Ventures West 8 Limited Partnership | AQXP | Series B-1 Special Voting Stock | D | 1,834,025 | ||||||||
| 2014-03-06 | 3 | Ventures West 8 Limited Partnership | AQXP | Series B-2 Special Voting Stock | D | 1,832,522 | ||||||||
| 2014-03-06 | 3 | Ventures West 8 Limited Partnership | AQXP | Common Special Voting Stock | D | 1,511,132 | ||||||||
| 2014-03-06 | 3 | Ventures West 8 Limited Partnership | AQXP | Series A- Special Voting Stock | D | 1,791,577 | ||||||||
| 2014-03-06 | 3 | Ventures West 8 Limited Partnership | AQXP | Series A-2 Special Voting Stock | D | 1,696,880 | ||||||||
| 2014-03-06 | 3 | Ventures West 8 Limited Partnership | AQXP | Series B-1 Special Voting Stock | D | 1,834,025 | ||||||||
| 2014-03-06 | 3 | Ventures West 8 Limited Partnership | AQXP | Series B-2 Special Voting Stock | D | 1,832,522 | ||||||||
| 2014-03-06 | 3 | Ventures West 8 Limited Partnership | AQXP | Series C Special Voting Stock | D | 1,886,273 | ||||||||
| 2014-03-06 | 3 | Ventures West 8 Limited Partnership | AQXP | Series C Special Voting Stock | D | 1,886,273 | ||||||||
| 2014-03-06 | 3 | Bridger Gary See Note (9) | AQXP | Series C Special Voting Stock | I | 1,886,273 | ||||||||
| 2014-03-06 | 3 | Bridger Gary See Note (9) | AQXP | Series C Special Voting Stock | I | 1,886,273 | ||||||||
| 2014-03-06 | 3 | Bridger Gary See Note (9) | AQXP | Series B-2 Special Voting Stock | I | 1,832,522 | ||||||||
| 2014-03-06 | 3 | Bridger Gary See Note (9) | AQXP | Series B-1 Special Voting Stock | I | 1,834,025 | ||||||||
| 2014-03-06 | 3 | Bridger Gary See Note (9) | AQXP | Series A-1 Special Voting Stock | I | 1,791,577 | ||||||||
| 2014-03-06 | 3 | Bridger Gary See Note (9) | AQXP | Common Special Voting Stock | I | 1,511,132 | ||||||||
| 2014-03-06 | 3 | Bridger Gary See Note (9) | AQXP | Series A-2 Special Voting Stock | I | 1,696,880 | ||||||||
| 2014-03-06 | 3 | Bridger Gary See Note (9) | AQXP | Series A-2 Special Voting Stock | I | 1,696,880 | ||||||||
| 2014-03-06 | 3 | Bridger Gary See Note (9) | AQXP | Series A-1 Special Voting Stock | I | 1,791,577 | ||||||||
| 2014-03-06 | 3 | Bridger Gary See Note (9) | AQXP | Common Special Voting Stock | I | 1,511,132 | ||||||||
| 2014-03-06 | 3 | Bridger Gary See Note (9) | AQXP | Series B-1 Special Voting Stock | I | 1,834,025 | ||||||||
| 2014-03-06 | 3 | Bridger Gary See Note (9) | AQXP | Series B-2 Special Voting Stock | I | 1,832,522 |
P
Compra de mercado aberto ou privada de ativo não-derivativo ou derivativo
S
Venda de mercado aberto ou privada de ativo não-derivativo ou derivativo
A
Concessão, premiação, ou outra aquisição de ativos da empresa (como uma opção)
C
Conversão de derivativo
D
Venda ou transferência de ativos de volta para a empresa
F
Pagamento do preço de exercício ou responsabilidade fiscal utilizando parte dos ativos recebidos da empresa
G
Doação de ativos pelo ou para o insider
K
Swaps de capital e transações de hedge similares
M
Exercício ou conversão de ativo derivativo recebido da empresa (como uma opção)
V
Uma transação voluntariamente reportada no Formulário 4
J
Outro (acompanhado de uma nota explicativa descrevendo a transação)
